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Sciences de la santé; Sciences médicales

Ovidiu Lungu

Recherche fondamentale et clinique en vieillissement, santé mentale et maladies neurodégénératives.

Professeur associé

Faculté de médecine - Département de psychiatrie et d’addictologie

o.lungu@umontreal.ca

Autre numéro : 514 340-3540 #3938 (Travail 1)

Portrait

Expertise de recherche

Recherche fondamentale: caractérisation de la neuroplasticité fonctionnelle dans le vieillissement, la santé mentale et les maladies neurodégénératives (focus: schizophrénie, maladie de Parkinson, démence). 

Recherche clinique: déterminants sociaux du vieillissement sain et pathologique et des maladies neurodégénératives - une double perspective: l'individu et son milieu de soins.

Biographie

- PhD in Psychology from "Al.I.Cuza" University, Iasi, ROMANIA (supervisor, Dr. Adrian NECULAU)

- Postdoctoral fellowship in neuroscience - Brain Sciences Center, University of Minnesota, USA (supervisor, Dr. James ASHE)

- Postdoctoral fellowship in neuroscience - Psychology Department, University of Montreal, CANADA (supervisor, Dr. Julien DOYON)

Prix et distinctions

  • Bourse postdoctorale (2007-2008) accordée par le Groupe de recherche sur le système nerveux central. 
  • Bourse de participation à ICPSR Summer School in Quantitative Methods, Ann Arbor MI, USA (juin-aout 2001) accordée par Soros Foundation Romania (HESP Program).
  • Bourse de stage au Princeton University, Princeton NJ, USA, offerte par the McDonnell Foundation, au sein du programme: “For the Advancement of Psychology in Romania” -  (printemps 1996).

Enseignement et encadrement

Projets

Projets de recherche

2020 - 2025

Characterizing and comparing sleep-related consolidation neurophysiological mechanisms for procedural and declarative memories (CIHR)

Chercheur principal : Julien Doyon
Co-chercheurs : Jean-Marc Lina , Julie Carrier , Habib Benali , Bradley King , Genevieve Albouy , Ovidiu Lungu
2020 - 2025

Characterizing & comparing sleep-related consolidation neurophysiological for procedural & declarative memories

Chercheur principal : Julien Doyon
Co-chercheurs : Ovidiu Lungu , Julie Carrier
Sources de financement : IRSC/Instituts de recherche en santé du Canada
Programmes de subvention : PVXXXXXX-(PJT) Subvention Projet
2016 - 2020

The PREvention Program for Alzheimer's RElated Delirium (PREPARED) Cluster Randomized Trial.

Chercheur principal : Machelle Wilchesky
Co-chercheurs : Ovidiu Lungu , Nathalie Champoux
Sources de financement : IRSC/Instituts de recherche en santé du Canada
Programmes de subvention : PVXXXXXX-(PJT) Subvention Projet
2014 - 2019

Canadian consortium on neurodegeneration in aging -full proposal (CCNA)

Chercheur principal : Howard Chertkow
Sources de financement : IRSC/Instituts de recherche en santé du Canada
Programmes de subvention :
2014 - 2019

Prevention and Treatment of Neuropsychiatric Symptoms - Canadian Consortium on Neurodegeneration in Aging (CCNA Team 11)

Chercheur principal : Howard Chertkow
Co-chercheurs : Ovidiu Lungu , Anne Bourbonnais , Marie Andrée Bruneau
Sources de financement : IRSC/Instituts de recherche en santé du Canada
Programmes de subvention :
2014 - 2015

RQRV - Non-pharmacological management of behavioral and psychological symptoms of dementia (BPSD) in long-term care: social determinants of adherence to clinical guidelines

Chercheur principal : Machelle Wilchesky , Philippe Voyer
Co-chercheurs : Ovidiu Lungu
Sources de financement : FRQS/Fonds de recherche du Québec - Santé (FRSQ)
Programmes de subvention : PVXXXXXX-Réseaux thématiques de recherche

Rayonnement

Publications et communications

Publications

       (citation H-index = 29 / i10-index = 49) - en juin 2020

       depuis 2014 (N=43 - en juin 2020)

  1. Solstrand Dahlberg L*, Lungu O, Doyon J. (2020) Cerebellar Contribution to Motor and Non-motor Functions in Parkinson's Disease: A Meta-Analysis of fMRI Findings. Frontiers in Neurolology. 2020;11:127. doi:10.3389/fneur.2020.00127
  2. Markova L, Bares M, Lungu O, & Filip P* (2020). Quantitative but Not Qualitative Performance Changes in Predictive Motor Timing as a Result of Overtraining. Cerebellum. doi:10.1007/s12311-019-01100-x
  3. Stip E*, Miron JP, Nolin M, Letourneau G, Bernazani O, Chamelian L, Boileau B, Gupta M, Luck D, Lungu O* (2019). Incidentaloma Discoveries in the Course of Neuroimaging Research. Can J Neurol Sci, 1-5. doi:10.1017/cjn.2018.397
  4. Gabitov E, Lungu O, Albouy G, & Doyon J.* (2019). Weaker Inter-hemispheric and Local Functional Connectivity of the Somatomotor Cortex During a Motor Skill Acquisition Is Associated With Better Learning. Front Neurol, 10, 1242. doi:10.3389/fneur.2019.01242
  5. Filip P*, Gallea C, Lehericy S, Lungu O, & Bares M. (2019). Neural Scaffolding as the Foundation for Stable Performance of Aging Cerebellum. Cerebellum. doi:10.1007/s12311-019-01015-7
  6. Pinsard B, Boutin A, Gabitov E, Lungu O, Benali H, & Doyon J.* (2019). Consolidation alters motor sequence-specific distributed representations. Elife, 8. doi:10.7554/eLife.39324
  7. Potvin S, Gamache L, & Lungu O.* (2019). A Functional Neuroimaging Meta-Analysis of Self-Related Processing in Schizophrenia. Front Neurol, 10, 990. doi:10.3389/fneur.2019.00990
  8. Tikasz A, Dumais A, Lipp O, Stip E, Lalonde P, Laurelli M, Lungu O, Potvin S.* (2019). Reward-related decision-making in schizophrenia: A multimodal neuroimaging study. Psychiatry Res Neuroimaging, 286, 45-52. doi:10.1016/j.pscychresns.2019.03.007
  9. Zemankova P, Losak J, Czekoova K, Lungu O, Jani M, Kasparek T, & Bares M.* (2018). Theory of Mind Skills Are Related to Resting-State Frontolimbic Connectivity in Schizophrenia. Brain Connect, 8(6), 350-361. doi:10.1089/brain.2017.0563
  10. Potvin S*, Tikasz A, Richard-Devantoy S, Lungu O, & Dumais A. (2018). History of Suicide Attempt Is Associated with Reduced Medial Prefrontal Cortex Activity during Emotional Decision-Making among Men with Schizophrenia: An Exploratory fMRI Study. Schizophr Res Treatment, 2018, 9898654. doi:10.1155/2018/9898654
  11. Nadeau A, Lungu O, Bore A, Plamondon R, Duchesne C, Robillard ME, . . . Doyon J.* (2018). A 12-Week Cycling Training Regimen Improves Upper Limb Functions in People With Parkinson's Disease. Front Hum Neurosci, 12, 351. doi:10.3389/fnhum.2018.00351
  12. Laventure S, Pinsard B, Lungu O, Carrier J, Fogel S, Benali H, . . . Doyon J.* (2018). Beyond spindles: interactions between sleep spindles and boundary frequencies during cued reactivation of motor memory representations. Sleep, 41(9). doi:10.1093/sleep/zsy142
  13. Tikasz A, Potvin S*, Richard-Devantoy S, Lipp O, Hodgins S, Lalonde P, Lungu O, Dumais A. (2017). Reduced dorsolateral prefrontal cortex activation during affective Go/NoGo in violent schizophrenia patients: An fMRI study. Schizophrenia research. doi: 10.1016/j.schres.2017.11.011
  14. Potvin S*, Lungu O, Tikasz A, & Mendrek A. (2017). Abnormal effective fronto-limbic connectivity during emotion processing in schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 72, 1-8. doi:10.1016/j.pnpbp.2016.08.004
  15. Ballard SA, Peretti M, Lungu O, Voyer P, Tabamo F, Alfonso L, Cetin-Sahin D, Johnson SMA, & Wilchesky, M.* (2017). Factors affecting nursing staff use of a communication tool to reduce potentially preventable acute care transfers in long-term care. Geriatric Nursing. doi:10.1016/j.gerinurse.2017.03.012
  16. Potvin S*, Tikasz A, Lungu O, Stip E, Zaharieva V, Lalonde P, Lipp O, & Mendrek,A. (2017). Impaired Coupling between the Dorsomedial Prefrontal Cortex and the Amygdala in Schizophrenia Smokers Viewing Anti-smoking Images. Frontiers in Psychiatry, 8. doi:10.3389/fpsyt.2017.00109
  17. Nadeau A, Lungu O, Duchesne C, Robillard ME, Bore A, Bobeuf F, Plamondon R, Lafontaine A-L, Gheysen F, Bherer L, & Doyon J.* (2017). A12-Week Cycling Training Regimen Improves Gait and Executive Functions Concomitantly in People with Parkinson's Disease. Frontiers in Human Neuroscience, 10. doi:10.3389/fnhum.2016.00690
  18. Filip P*, Gallea C, Lehericy S, Bertasi E, Popa T, Marecek R, Lungu O, Kasparek T, Vanicek J, & Bares M. (2017). Disruption in cerebellar and basal ganglia networks during a visuospatial task in cervical dystonia. Movement Disorders, 32(5), 757-768. doi:10.1002/mds.26930
  19. Fogel,S, Albouy G, King BR, Lungu O, Vien C, Bore A, Pinsard B, Benali H, Carrier J, & Doyon J. (2017). Reactivation or transformation? Motor memory consolidation associated with cerebral activation time-locked to sleep spindles. PLoS One, 12(4), e0174755. doi:10.1371/journal.pone.0174755
  20. Stip E, Cherbal A, Luck D, Zhornitsky S, Bentaleb LA, & Lungu O.* (2017). A neuroimaging study of emotion-cognition interaction in schizophrenia: the effect of ziprasidone treatment. Psychopharmacology (Berl), 234(7), 1045-1058. doi:10.1007/s00213-017-4533-9
  21. Vien C, Bore A, Lungu O, Benali H, Carrier J, Fogel S, & Doyon J.* (2016). Age-related white-matter correlates of motor sequence learning and consolidation. Neurobiology of Aging, 48, 13-22. doi:10.1016/j.neurobiolaging.2016.08.006
  22. Laventure S, Fogel S, Lungu O, Albouy G, Sévigny-Dupont P, Vien C, Sayour C, Carrier J, Benali H, & Doyon J* (2016). NREM2 and Sleep Spindles Are Instrumental to the Consolidation of Motor Sequence Memories. PLoS Biol. 14(3):e1002429. doi: 10.1371/journal.pbio.1002429. PubMed PMID: 27032084.
  23. Potvin S*, Lungu O, Lipp O, Lalonde P, Zaharieva V, Stip E, Melun JP, Mendrek A (2016). Increased ventro-medial prefrontal activations in schizophrenia smokers during cigarette cravings. Schizophr Res. 173(1-2):30-6. doi: 10.1016/j.schres.2016.03.011. Epub 2016 Mar 19. PubMed PMID: 27005897.
  24. Zemankova P, Lungu O*, Bares M* (2016). Psychosocial Modulators of Motor Learning in Parkinson's Disease. Front Hum Neurosci. 10:74. doi: 10.3389/fnhum.2016.00074. eCollection 2016. Review. PubMed PMID: 26973495.
  25. Lungu OV*, Bares M, Liu T, Gomez CM, Cechova I, Ashe J (2016). Trial-to-trial Adaptation: Parsing out the Roles of Cerebellum and BG in Predictive Motor Timing. J Cogn Neurosci. 4:1-15. [Epub ahead of print] PubMed PMID: 26942317.
  26. de Almeida RG*, Riven L, Manouilidou C, Lungu O, Dwivedi VD, Jarema G, & Gillon B. (2016). The Neuronal Correlates of Indeterminate Sentence Comprehension: An fMRI Study. Front Hum Neurosci, 10, 614. doi:10.3389/fnhum.2016.00614
  27. Duchesne, C, Gheysen, F, Bore, A, Albouy, G, Nadeau, A, Robillard, M. E, Bobeuf, F, Lafontaine, A. L, Lungu, O, Bherer, L, Doyon, J.* (2016). Influence of aerobic exercise training on the neural correlates of motor learning in Parkinson's disease individuals. Neuroimage Clin, 12, 559-569. doi:10.1016/j.nicl.2016.09.011
  28. Tikasz A, Potvin S, Lungu O, Joyal CC, Hodgins S, Mendrek A, & Dumais A.* (2016). Anterior cingulate hyperactivations during negative emotion processing among men with schizophrenia and a history of violent behavior. Neuropsychiatr Dis Treat, 12, 1397-1410. doi:10.2147/ndt.s107545
  29. Zemankova P, Lungu O, Huttlova J, Kerkovsky M, Zubor J, Lipova P, . . . Bares M* (2016). Neuronal substrate and effective connectivity of abnormal movement sequencing in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry, 67, 1-9. PMID: 26780603
  30. Filip P*, Lungu OV, Manto MU, & Bares M (2015). Linking essential tremor to the cerebellum: physiological evidence. Cerebellum. Nov 3. [Epub ahead of print] PMID: 26530223
  31. Lungu O*, Potvin S, Tikasz A, Mendrek A (2015). Sex differences in effective fronto-limbic connectivity during negative emotion processing. Psychoneuroendocrinology 2015 Aug 17; 60(3 supplement 2):S35-S39. PMID: 25886678
  32. Duchesne C, Lungu O, Nadeau A, Robillard ME, Boré A, Bobeuf F, Lafontaine AL, Gheysen F, Bherer L, Doyon J* (2015). Enhancing both motor and cognitive functioning in Parkinson's disease: Aerobic exercise as a rehabilitative intervention. Brain and Cognition 2015 Oct;99:68-77. doi: 10.1016/j.bandc.2015.07.005. Epub 2015 Aug 7 PMID: 26263381
  33. Potvin S*, Tikasz A, Lungu O, Dumais A, Stip E, Mendrek A (2015). Emotion processing in treatment-resistant schizophrenia patients treated with clozapine: An fMRI study. Schizophr Res. Aug 5. pii: S0920-9964(15)00412-0. doi: 10.1016/j.schres.2015.07.046. [Epub ahead of print]. PMID: 26255082
  34. Vahdat S*, Lungu O*, Cohen-Adad J, Marchand-Pauvert V, Benali H, Doyon J (2015). Simultaneous Brain-Cervical Cord fMRI Reveals Intrinsic Spinal Cord Plasticity during Motor Sequence Learning. PLoS Biology Jun 30;13(6):e1002186. doi: 10.1371/journal.pbio.1002186. eCollection 2015 Jun. PMID: 26125597
  35. Cavallo A, Lungu O, Becchio C, Ansuini C, Rustichini A*, Fadiga L* (2015). When gaze opens the channel for communication: Integrative role of IFG and MPFC. NeuroImage Oct 1;119:63-9. doi: 10.1016/j.neuroimage.2015.06.025. Epub 2015 Jun 12. PMID: 26080312
  36. Stip E*, Lungu OV* (2015). Salience Network and Olanzapine in Schizophrenia: Implications for Treatment in Anorexia Nervosa. Canadian journal of psychiatry / Revue canadienne de psychiatrie Mar 1; 62:180-188. doi: 10.1016/j.psyneuen.2015.08.012. [Epub ahead of print] PMID: 26318628
  37. Wilchesky M, & Lungu O* (2015). Predictive and Concurrent Validity of the Braden Scale in Long-Term Care: A Meta-Analysis. Wound Repair Regen. doi:10.1111/wrr.12261
  38. Potvin S*, Lungu OV, Stip E* (2015). Anandamide is involved in appetite-related amygdala hyperactivations in schizophrenia patients treated with olanzapine: a functional magnetic resonance imaging study. Journal of clinical psychopharmacology Feb;35(1):82-3. PMID: 25370126
  39. Sylvain-Roy S, Lungu O, & Belleville S. (2015). Normal Aging of the Attentional Control Functions That Underlie Working Memory. J Gerontol B Psychol Sci Soc Sci, 70(5), 698-708. doi:10.1093/geronb/gbt166
  40. Potvin S Lungu O & Stip E*. (2014). Anandamide is a peripheral biomarker of the sensitized amygdala responses to food cues in schizophrenia: an fmri study. Biological Psychiatry 75: 111S-11S
  41. Lungu O*, Monchi O, Albouy G, Jubault T, Ballarin E, Burnod Y, . . . Doyon J. (2014) Striatal and hippocampal involvement in motor sequence chunking depends on the learning strategy. PloS ONE. 2014;9(8):e103885. PubMed PMID: 25148078. Pubmed Central PMCID: 4141721.
  42. Sylvain-Roy S, Lungu O, Belleville S.* (2014) Normal Aging of the Attentional Control Functions That Underlie Working Memory. The journals of gerontology Series B, Psychological sciences and social sciences. 2014 Jan 27. PubMed PMID: 24470174.
  43. Husarova I, Lungu OV, Marecek R, Mikl M, Gescheidt T, Krupa P, . . . Bares M*. (2014) Functional imaging of the cerebellum and basal ganglia during predictive motor timing in early Parkinson's disease. Journal of neuroimaging: official journal of the American Society of Neuroimaging. 2014 Jan-Feb;24(1):45-53. PubMed PMID: 22211726.

Disciplines

  • Psychiatrie
  • Neurosciences
  • Gérontopsychiatrie
  • Psychologie

Champ d’expertise

  • Cognition
  • Démences
  • Développement cognitif
  • Déterminants sociaux de la santé
  • Interactivité
  • Neuropsychologie cognitive du vieillissement
  • Soins de longue durée
  • Apprentissage et mémoire (Psychologie - aspects biologiques)
  • Maladie de Parkinson
  • Schizophrénie
  • Soins hospitaliers
  • Maladies neurodégénératives (Vieillissement)
  • Qualité de vie et vieillissement