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Sciences de la santé; Sciences de la vie

Daniel Thirion

Pharmacien expert en maladies infectieuses et antibiogouvernance (Antibiotic stewardship).

Professeur titulaire de clinique

Faculté de pharmacie

Pavillon Jean Coutu, local 2181

514 343-6111 #5207

daniel.thirion@umontreal.ca

Autre numéro : 514 343-6120 (Télécopieur)

Portrait

Expertise de recherche

Pharmacien expert en maladies infectieuses et antibiogouverance. A completé la formation de B.Pharm. et M.Sc. à la Faculté de pharmacie de l'Université de Montréal, puis un PharmD de 3e cycle à Wayne State University à Detroit, suivi d'une formation spécialisée en maladies infectieuses à UCSF. Pratique active au Centre universitaire de santé McGill en pharmacocinétique et en antibiogouvernance. Enseignement en maladies infectieuses, microbiologie médicale, soins pharmaceutiques - pharmacocinétique - pharmacothérapie en maladies infectieues, antibiogouvernance dans les programmes de 1er à 3e cycle de la Faculté de pharmacie. Recherche orientée sur l'impact des interventions sur la résistance aux antibiotiques et l'usage optimale des anti-infectieux. Récipiendaire de prix d'excellence dans l'ensemble des sphères de travail.

Prix et distinctions

2019      Prix d'excellence en innovation 2019: Ordre des pharmaciens du Québec

2019      Prix Marie Pineau Françcois Schubert pour excellence en recherche 2019: Institut de recherche du Centre universitaire de santé McGill

2017      Prix d'excellence en enseignement 2017: Faculté de pharmacie, Université de Montréal

2017      Prix Hippocrate 2017: mention honorable; pour travail en interdisciplinité

2017      Prix d'excellence A.P.E.S. 2017: Leadership en matière d'innovation

2017      Prix QuintilesIMS 18e édition: Pour excellence d'un artilce sur l'utilisation efficiente de medicaments

2016      Prix Profession Santé  Pratique novatrice pharmacien; Groupe Santé de Rogers Média            

2014      Prix d’excellence en pratique spécialisée TEVA Canada – A.P.E.S.; Association des pharmaciens en établissements de santé

2013      AFPC Past President’s award for  presidency of AFPC 2012-2013; Association des facultés de pharmacie du Canada

2013      Prix de reconnaissance de l'innovation   Pfizer-A.P.E.S.; Programme de parrainage des antimicrobiens; Association des pharmaciens en établissements de santé

2010      Best article for patient safety; Les allergies croisées aux antibiotiques; IMS Health

2008      Fellow of the Canadian Society of Hospital Pharmacists; Canadian Society of Health System Pharmacists       

2005      Prix de reconnaissance de l'innovation en support  à la pratique Pfizer-A.P.E.S. 2004; Snippets for Snappy Antimicrobial Therapy; ssociation des pharmaciens en établissements de santé

Formation

  • 2001 — Résidence spécialisé en maladies infectieuses — — University of California, San Francisco
  • 1999 — Pharm.D. — PharmacieWayne State University
  • 1997 — M.Sc. — PharmacieUniversité de Montréal
  • 1996 — B.Pharm. — — Université de Montréal

Affiliations et responsabilités

Titres professionnels et autres affiliations

Activités clinique et professionnelle

Pharmacien expert en maladies infectieuses au Centre universitaire de santé McGill

Enseignement et encadrement

Enseignement

Projets

Rayonnement

Publications et communications

Publications

Articles révisés par les pairs (5 dernières années)

Lombardi J,Nguy P, Robichaud Ducharme A, et al. Assessment of Surgical Antibiotic Prophylaxis Compliance in Pediatrics (ASAP-P): A Pre-Post Quasi-Experimental Study. Pediatr Infect Dis J. 2020;39(1):48-53

Thirion DJG, Pasche V, Marsot A. What is the recommended amikacin dosing for cystic fibrosis patients with acute pulmonary exacerbations? Ped Pulmonol. 2019;54(11):1652-1653.

Lee SB, Thirion DJG, Irfan N, et al. Antimicrobial utilization data : Does point prevalence data correlate with defined daily doses? Infect Control Hosp Epidemiol 2019;11:1-2.

Morris AM, Rennert-May E, Dalton B, Daneman N, et al. Rationale and development of a business case for antimicrobial stewardship programs in acute care hospital settings. Antimicrob Resist Infect Control 2018;7:104.

Dolcé L, Quach C, Thirion DJG, et al. Surveillance of Antimicrobial Use in Quebec Acute Care Hospitals : A Survey. JAMMI 2018;3.1:37-46.

Le Saux N, Dalton B, Abbass K, et al. Funding for Antimicrobial Stewardship Programs: A Customizable Business Case Template. Can J Hosp Pharm 2018;71: 50-51.

Association des pharmaciens des établissements de santé du Québec (A.P.E.S.). Rôle du pharmacien d’établissement en infectiologie : Données probantes. Document élaboré par le Regroupement de pharmaciens experts en infectiologie. Montréal, Québec : A.P.E.S.;2018. 52 p.

Mavrakanas TA, Fournier MA, Clairoux S, Amiel JA, Tremblay ME, Vinh DC, et al. Neutropenia in kidney and liver transplant recipients: Risk factors and outcomes. Clinical Transplantation 2017;31(10):e13058.

Frenette C, Sperlea D, Leharova Y, Thirion DJG. Impact of an Infection Control and Antimicrtobial Stewardship Program on Solid Organ Transplantation and Hepatobiliary Surgical Site Infections. Infect Control Hosp Epidemiol 2016;37(12):1468-1474.

Frenette C, Sperlea D, Tesolin J, Patterson C, Thirion DJG. Impact of a 5-year serial infection control and antibiotic stewardship intervention on cardiac surgical site infections. Am J Infect Control 2016;44:977-82

Carle S, Thirion DJG. La procalcitonine est-elle vraiment utile comme aide à la decision de prescrire ou non des antibiotiques chez les patients de soins critiques. Pharmactuel 2016;49(2)

Livres et chapitres de livres (5 dernières années)

Thirion DJG. Chap 63 :Antimicrobial Prophylaxis for Surgical Procedures. In: Koda-Kimble MA, Young LY, Alldredge BK, Corelli RL, Guglielmo BJ, Kradjan WA, et al. eds. Applied Therapeutics; The Clinical Use of Drugs. 11th  ed. Philadelphia, Lippincott Williams & Wilkins: 2016 (In press).

Thirion DJG. Acute Cough. Dans: Repchinksy C, ed. Therapeutic Choices for Minor Ailments. 2nd ed. Canadian Pharmacists’ Association, Ottawa ON. 2016 pages 212-220.

Thirion DJG. Assessment of Patients with Upper Respiratory Tract Infections. Dans: Repchinksy C, ed. Therapeutic Choices for Minor Ailments. 2nd ed. Canadian Pharmacists’ Association, Ottawa ON. 2016 pages 245-249.

Thirion DJG. Viral Rhinitis, Influenza, Sinusitis and Pharyngitis. Dans: Repchinksy C, ed. Therapeutic Choices for Minor Ailments. 2nd ed. Canadian Pharmacists’ Association, Ottawa ON. 2016 pages 250-268.

Afshar K, Bedford J, Chan T, Flintoft V, Fryters S, Glenn N, et al. Prevent Surgical Site Infections. Getting Started Kit. Safer Healthcare Now!  Canadian Patient Safety Institute. August 2014

Thirion DJG. Antimicrobial Prophylaxis for Ambulatory Surgery. Dans Dong BJ, Elliott DP, eds. Infection Primary Care 1, Ambulatory Care Self-Assessment Program (ACSAP). American College of Clinical Pharmacy. 2013, pages 7-17.

Thirion’s Snippets for Snappy Antimicrobial Therapy, 3rd ed. Thirion DJG, éd. Publications PRISM., Montréal 2013, 352 pages.

Thirion DJG. Basics in Antimicrobial Therapy Dans: Thirion’s Snippets for Snappy Antimicrobial Therapy, 3rd ed. Thirion DJG, éd. Publications PRISM, Montréal. 2013, pages 2-5.

Thirion DJG. Bacterial Resistance and Antimicrobial Therapy. Thirion’s Snippets for Snappy Antimicrobial Therapy, 3rd ed. Thirion DJG, éd. Publications PRISM, Montréal. 2013, pages 6-11.

Thirion DJG. Acute Rhinosinusitis. Dans: Thirion’s Snippets for Snappy Antimicrobial Therapy, 3rd ed. Thirion DJG, éd. Publications PRISM, Montréal. 2013, pages 60-63.

Thirion DJG. The Common Cold and the Flu. Dans: Thirion’s Snippets for Snappy Antimicrobial Therapy. Thirion DJG, éd. Publications PRISM, Montréal. 2013, pages 64-67.

Thirion DJG. Pharyngitis. Dans: Thirion’s Snippets for Snappy Antimicrobial Therapy, 3rd ed. Thirion DJG, éd. Publications PRISM, Montréal. 2013, pages 68-70.

Thirion DJG. Hospital Acquired Pneumonia-Ventilator Associated Pneumonia. Dans: Thirion’s Snippets for Snappy Antimicrobial Therapy, 3rd ed. Thirion DJG, éd. Publications PRISM, Montréal. 2013, pages 111-119.

Zoé Thiboutot, Thirion DJG, Williamson DR. Peritonitis. Dans: Thirion’s Snippets for Snappy Antimicrobial Therapy, 3rd ed. Thirion DJG, éd. Publications PRISM, Montréal. 2013, pages 137-141.

Thirion DJG. Urinary Tract Infections and Prostatitis. Dans: Thirion’s Snippets for Snappy Antimicrobial Therapy, 3rd ed. Thirion DJG, éd. Publications PRISM, Montréal. 2013, pages 163-168.

Thirion DJG. Invasive Fungal Infections. Dans: Thirion’s Snippets for Snappy Antimicrobial Therapy, 3rd ed. Thirion DJG, éd. Publications PRISM, Montréal. 2013, pages 228-233.

Thirion DJG. Superficial Fungal Infections. Dans: Thirion’s Snippets for Snappy Antimicrobial Therapy, 3rd ed. Thirion DJG, éd. Publications PRISM, Montréal. 2013, pages 234-243.

Thirion DJG. Antimicrobial Drug Interactions. Dans: Thirion’s Snippets for Snappy Antimicrobial Therapy, 3rd ed. Thirion DJG, éd. Publications PRISM, Montréal. 2013, pages 270-282.

Thirion DJG. Antibiotic Combination Therapy. Dans: Thirion’s Snippets for Snappy Antimicrobial Therapy, 3rd ed. Thirion DJG, éd. Publications PRISM, Montréal. 2013, pages 287-288.

Thirion DJG. Antibiotic Prophylaxis for Surgery. Dans: Thirion’s Snippets for Snappy Antimicrobial Therapy, 3rd ed. Thirion DJG, éd. Publications PRISM, Montréal. 2013, pages 306-309.

Thirion DJG. Antifungal Agents for Invasive Fungal Infections. Dans: Thirion’s Snippets for Snappy Antimicrobial Therapy, 3rd ed. Thirion DJG, éd. Publications PRISM, Montréal. 2013, pages 340-343.

Thirion DJG. Acute Cough. Dans: Repchinksy C, ed. Therapeutic Choices for Minor Ailments. 1st ed. Canadian Pharmacists’ Association, Ottawa ON. 2013 pages 207-214.

Thirion DJG. Assessment of Patients with Upper Respiratory Tract Infections. Dans: Repchinksy C, ed. Therapeutic Choices for Minor Ailments. 1st ed. Canadian Pharmacists’ Association, Ottawa ON. 2013 pages 175-178.

Thirion DJG. Viral Rhinitis, Influenza, Sinusitis and Pharyngitis. Dans: Repchinksy C, ed. Therapeutic Choices for Minor Ailments. 1st ed. Canadian Pharmacists’ Association, Ottawa ON. 2013 pages 194-206.

Thirion DJG, Carle S. Recommendations pour la mise en œuvre d’un programme de parrainage des antimicrobiens en établissement de santé. Guide de pratique pour l’Association des Pharmaciens en Établissements de Santé. www.apesquebec.org  04/2012

Mise en œuvre d’un programme de surveillance de l’usage des antibiotiques en établissement de santé, Normes et pratiques de gestion, Tome II. MSSS, Gouvernement du Québec. Circulaire 2011-021

Thirion DJG. Chap 61 :Antimicrobial Prophylaxis for Surgical Procedures. Dans: Koda-Kimble MA, Young LY, Alldredge BK, Corelli RL, Guglielmo BJ, Kradjan WA, et al. éd. Applied Therapeutics; The Clinical Use of Drugs. 10e éd. Philadelphie, Lippincott Williams & Wilkins: 2012;1461-1467.

Communications

Thirion DJG, Lanfranchi C, Deda A, et al. Ciprofloxacin versus ciprofloxacin and aminoglycoside for prevention of systemic inflammatory response syndrome, bacteraemia, sepsis and septic shock in transrectal ultrasound-guided prostate biopsy. Abstract 1389. 29th European Congress of Clinical Micorbiology and Infectious Diseases (ECCMID), Amsterdam, Pays Bas 13-16/04/2019

Fortin E, Thirion DJG, Ouakki M, et al. Could variations in antimicrobial use explain a major decline in rates of healthcare-associated Clostridium difficile infections in Québec, Canada? Abstract 6118. 29th European Congress of Clinical Micorbiology and Infectious Diseases (ECCMID), Amsterdam, Pays Bas 13-16/04/2019

Rudnick W, L Pelude, K Abdesselam, et al. Antimicrobial Use among Adult Inpatients at Canadian Nosocomial Infection Surveillance Program (CNISP) Hospital Sites across Canada, 2009 to 2016. Abstract C05. AMMI Canada/CACMID Annual Conference 2019, Ottawa, Canada, 4-6/04/2019.

Abdesselam K, Pelude L, Laverty M, Amaratunga K, Comeau J, Dalton B, Embree J, Evans GA, Forrester L, Frenette C, Fryters S, German G, Grant J, Gravel D, Katz K, Kibsey P, Lee BE, Lefebvre M-A, Leis JA, McGeer A, McKenna S, Mulvey MR, Neville H, Nixon K, Simor AE, Slater K, Suh H, Weiss K, Thirion D, Science M, Conly JM, CNISP participating hospitals. Quantitative Antimicrobial Usage Surveillance from 2009–2015 among Hospitals Participating in the Canadian Nosocomial Infection Surveillance Program (CNISP). AMMI Canada/CACMID Annual Conference 2018, Vancouver, Canada, May 2-5, 2018. JAMMI 2018;3(S1):51-2.

Lee SB, Thirion D, Irfan N, Sung M, Brooks A, Frenette C, Mertz D. Antimicrobial Utilization Data: Does Point Prevalence Data Correlate with Defined Daily Doses (DDD)? AMMI Canada/CACMID Annual Conference 2018, Vancouver, Canada, May 2-5, 2018. JAMMI 2018;3(S1):122.

Glass-Kaastra S, Conly JM, German G, Morris AM, Patrick DM, Thirion D, Weiss K, Gravel D. Use of oral and parenteral antimicrobials of last resort in Canada according to the WHO essential medicines list. AMMI Canada/CACMID Annual Conference 2018, Vancouver, Canada, May 2-5, 2018. JAMMI 2018;3(S1):50-1.

Glass-Kaastra S, Taylor JC, Conly JM, Arthur J, German G, Morris AM, Patrick DM, Thirion D, Weiss K, Gravel D. Antimicrobial prescribing by dentists, nurses, and pharmacists in the ambulatory setting in Canada. AMMI Canada/CACMID Annual Conference 2018, Vancouver, Canada, May 2-5, 2018. JAMMI 2018;3(S1):52.

Glass-Kaastra S, Conly JM, German G, Morris AM, Patrick DM, Thirion D, Weiss K, Gravel D. Measurement of parenteral and oral antimicrobial usage in Canadian hospitals via assessment of purchasing data. AMMI Canada/CACMID Annual Conference 2018, Vancouver, Canada, May 2-5, 2018. JAMMI 2018;3(S1):20-1.

Abdeesselam K, Conly J, Evans G, German G, Katz K, Kibsey P, McGeer A, Pelude L, Simor A, Suh K, Thirion D, Weiss K, Amartaunga K, Gravel D, and the Canadian Nosocomial Infection Surveillance Program (CNISP). Quantitative Antimicrobial Usage Surveillance Amongst CNISP Hospital Sites across Canada : Pilot Study REsults 2009 to 2013. AMMI Canada/CACMID Annual Conference 2017. Toronto, Canada  May 4, 2017

Rachel S, Thirion DJG, Frenette C. Reducing surgical site infections in neurosurgery : a multidisciplinary approach. APIC 44th Annual Conference. Portland, OR June 15th 2017. EPOP-157. Am J Infect Control 2017;45(6)Suppl.:S110

Mavrakanas T, Coursol C, Vinh DC, Thirion DJG, Cantarovich M. Neutropenia in kidney and liver transplant recipients : Risk factors and consequences. Abstract 1729. 2017 American Transplant Congress (ATC). Chicago, IL, April 2017.

Richard ME, Tisnado-Garland C, Frenette C, Thirion DJG. Attributable inpatient costs of nosocomial Clostridium difficile infection in a Canadian tertiary care center. Abstract 2339. 27th European Congress of Clinical Microbiology and Infectious Diseaes 2017, Vienna, Austria, April 2017.

Longpré AA, Maurrasse RK, Monast PO, Vujanovic S, Carle S, Guévremont C, Frenette C, Thirion DJG. Impact of an Antimicrobial Stewardship Program on Surgical Antibiotic Prophylaxis Conformity According to 2013 ASHP/IDSA Guidelines, Abstract 49957 IDWeek 2015, SanDiego, CA, US, Octobre 2015. Open Forum Infect Dis 2015;2(suppl1) : doi: 10.1093/ofid/ofv133.979

Fortin E, Thirion DJG, Bergeron L, Gonzales M, Papenburg J, Dionne M, Quach C. Surveillance of Antimicrobial Use in Québec Acute Care Hospitals : A Dream or Almost Reality? Presented at : Canadian Association of Clinical Microbiologists and Infections Diseases Annual Conference, Charlottetown, Canada, 04/2015.

Ducepppe MA, Thirion DJG. Antimicrobial spectra of activity chart based on North American susceptibility data. Presented at : International Union of Microbiological Societies 2014 Congresses, Montreal, Canada, 06/2014.

Clairoux S, Amiel JA, Tremblay ME, Fournier MA, Coursol C, Vinh D, Cantarovich M, Thirion DJG. Risk Factors, Rejection and Infections Associated with Neutropenia in Solid Organ Transplantation : A Retrospective Study. Présenté à American Transplant Congress 2013.

Disciplines

  • Pharmacie
  • Infectiologie

Champ d’expertise

  • Axe : Pharmacométrie et pharmacothérapie
  • Pharmacothérapie (maladies infectieuses)
  • Résistance aux antimicrobiens
  • Parrainage des antimicrobiens
  • Antibiotiques et résistance