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Health Sciences; Medical Sciences

Raja Hatem

Interventional Cardiologist with an expertise in complex coronary disease and CTOs

Professeur adjoint de clinique

Faculté de médecine - Département de médecine


Sensei Podcast Interview


Research expertise

In addition to teaching and clinical research, Dr. Hatem focuses on the treatment of coronary artery disease, particularly the percutaneous approach to chronically occluded coronary artery (CTO) debridement and other complex hemodynamic procedures (CHIP).


Graduated of the University of Montreal in 2009, Dr. Raja Hatem completed his residency in internal medicine and cardiology in teaching hospitals at the same university in 2015.

Subsequently, he undertook additional training in interventional cardiology (hemodynamics) and more precisely in complex high-risk procedures at the prestigious Columbia University in New York.

In addition to teaching and clinical research, Dr. Hatem focuses on the treatment of coronary artery disease, particularly the percutaneous approach to chronically occluded coronary artery (CTO) debridement and other complex hemodynamic procedures (CHIP).

He is a national and international lecturer in his field and contributed to co-write many chapters in interventional cardiology reference books.

He is currently cath lab director and director of the CTO-CHIP program at the Sacré Coeur Hospital part of the CIUSSS North on the Island of Montreal

Awards and recognitions

  • University of Montreal’s Physiology Department bursary recipient for the summer of 2004 
  • Bric-Pfizer’s bursary recipient for medical implication in the community in 2008 
  • Personality of the year award in medical school year 2009 
  • Sacré-Coeur Hospital’s Internal Medicine competition research bursary recipient in 2012 
  • 1st prize at Montreal’s Heart Institute research competition day in 2013 
  • Chief Resident at the Montreal Heart Institute for the 2014-2015 academic year
  • Valedictorian Speech at Specialists Graduation Ceremony in 2015
  • Bayer’s fellowship bursary recipient 2015-2016 
  • First operator in Canada to use the SyncVision iFR coregistration system (Philipps) in 12-2018
  • First operator in Canada to use the Mamba microcatheter family of products (Boston Scientific) in 08-2020
  • First operator in Canada to use the MicroRx microcatheter (IMDS-Biotronik) in 03-2024


  • 2017 — Cardiologie Interventionnelle (Hémodynamie) — — Columbia University Medical Center
  • 2015 — Cardiologie — — Université de Montréal
  • 2013 — Médecine Interne — — Université de Montréal
  • 2009 — Médecine — — Université de Montréal

Affiliations and responsabilities

Research affiliations

Affiliated institutions

  • CIUSSS du Nord-de-l'Île-de-Montréal – Hôpital du Sacré-Cœur de Montréal (HSCM)

University service and activities

Administrative responsibilities

Chef du laboratoire d'hémodynamique

Directeur du programme CHIP-CTO

Teaching and supervision



Expertise professionnelle (hors de l’institution)

Conférencier invité à des conférences nationales et internationales

Publications and presentations


●      The transformation of a unilateral locomotor command into a symmetrical bilateral activation in the brainstem. The Journal of Neuroscience. 2010 Jan 13; 30(2):523-33. Brocard F, Ryczko D, Fénelon K,  Hatem R, Gonzales D, Auclair F, Dubuc R

●      Porcine model of intracoronary pulverization of stent struts by rotablation atherectomy and its effects on microvasculature. Catheter Cardiovasc Interv. 2013 Dec 1;82(7):E842-8. Quang TT, Hatem R, Rousseau G, Dube B, Samson C, Schampaert E, Charron T 

●      Dual effect of pre-ischemic administration of TNF-alpha on myocardial infarct size. World Journal of Cardiovascular Diseases, 2013, 3, 21-25. Thuy Tran Quang, Raja Hatem, Guy Rousseau, Audrey-Anne  Gosselin, Erick Schampaert, Thierry Charron 

●      Effect of Radial-to-Femoral Access Crossover on Adverse Outcomes in Primary Percutaneous Coronary Intervention. Am J Cardiol. 2014 Oct 15;114(8):1165-73. Azzalini L, Khan R, Al-Hawwas M, Hatem R, Fortier A, L'Allier PL, Ly HQ 

●      Prognostic impact of the residual SYNTAX score on in-hospital outcomes in patients undergoing primary percutaneous coronary intervention. Catheter Cardiovasc Interv. 2016 Nov;88(5):740-747. Khan R, Al-Hawwas M, Hatem R, Azzalini L, Fortier A, Jolicoeur EM, Tanguay J F, Lavoie-L'Allier P, Ly HQ. 

●     Predictors of Excess Patient Radiation Exposure During Chronic Total Occlusion Coronary Intervention: Insights From a Contemporary Multicentre Registry. Can J Cardiol. 2016 Nov 11. pii: S0828-282X(16)31086-8.  [Epub ahead of print]. Christakopoulos GE, Christopoulos G, Karmpaliotis D, Alaswad K, Yeh RW, Jaffer FA, Wyman MR, Lombardi WL, Tarar MN, Grantham JA, Kandzari DE, Lembo N, Moses JW, Kirtane AJ, Parikh M, Green P, Finn M, Garcia S, Doing AH, Hatem R, Thompson CA, Banerjee S, Brilakis ES. 

●      Chronic Total Occlusion Percutaneous Coronary Intervention. Current Cardiovascular Risk Reports 10(12) · December 2016. Christine J. Chung, Matthew T. Finn, Raja Hatem, Philip Green, Ajay J. Kirtane and Dimitri Karmpaliotis 

●      In-Stent CTO, Not as Easy as it Looks. JACC Cardiovasc Interv.2017 May 8;10(9):903-905.Karmpaliotis D, Hatem R. 

●      Intravascular Ultrasound Analysis of Intraplaque Versus Subintimal Tracking in Percutaneous Intervention for Coronary Chronic Total Occlusions and Association With Procedural Outcomes. JACC CI May 2017. Lei Song, MD, Akiko Maehara, MD, Matthew T. Finn, MD, Sanjog Kalra, MD, MSc, Jeffrey W. Moses, MD, Manish A. Parikh, MD, Ajay J. Kirtane, MD, SM, Michael B. Collins, MD, Tamim M. Nazif, MD, Khady N. Fall, MD, MPH, Raja Hatem, MD, Ming Liao, MA, Tiffany Kim, BA, Philip Green, MD, Ziad A. Ali, MD, DPhil, Candido Batres, MD, Martin B. Leon, MD, Gary S. Mintz, MD, Dimitri Karmpaliotis, MD, PhD

●      Potential Sunitinib-Induced Coronary Artery and Aortic Dissections. Can J Cardiol. 2017 Jun; 33(6):830.e17-830.e18.  Hatem R, Bebawi E, Schampaert E.

●      Predictive Scores of Success in CTO PCI: There Is No Substitute for Operator Experience and Skill. JACC Cardiovasc Interv. 2017 Jun 12;10(11):1099-1101. Lembo NJ, Hatem R, Karmpaliotis D.

●      Incidence, Treatment, and Outcomes of Coronary Perforation During Chronic Total Occlusion Percutaneous Coronary Intervention. Am J Cardiol. 2017 Oct 15;120(8):1285-1292. Danek BA, Karatasakis A, Tajti P, Sandoval Y, Karmpaliotis D, Alaswad K, Jaffer F, Yeh RW, Kandzari DE, Lembo NJ, Patel MP, Mahmud E, Choi JW, Doing AH, Lombardi WL, Wyman RM, Toma C, Garcia S, Moses JW, Kirtane AJ, Hatem R, Ali ZA, Parikh M, Karacsonyi J, Rangan BV, Khalili H, Burke MN, Banerjee S, Brilakis ES.

●      Retrograde CTO-PCI of Native Coronary Arteries Via Left Internal Mammary Artery Grafts: Insights From a Multicenter U.S. Registry. J Invasive Cardiol. 2018 Mar;30(3):89-96. Tajti P, Karatasakis A, Karmpaliotis D, Alaswad, K, Jaffer FA, Yeh RW, Patel M, Mahmud E, Choi JW, Doing AH, Toma C, Uretsky B, Garcia S, Moses JW, Parikh, M, Kirtane A, Ali ZA, Hatem R, Karacsonyi J, Danek BA, Rangan BV, Banerjee S, Ungi I, Brilakis ES.

●      Morphological Patterns of In-Stent Chronic Total Occlusions: An Intravascular Ultrasound Study. JACC Cardiovasc Interv. 2018 Apr 9;11(7):711-714. Yin D, Maehara A, Mintz GS, Song L, Finn MT, Hatem R, Amemiya K, Moses JW, Parikh MA, Kirtane AJ, Collins MB, Nazif TM, Fall KN, Liao M, Green P, Ali ZA, Batres C, Stone GW, Leon MB, Ochiai M, Karmpaliotis D

●      Zero contrast retrograde chronic total occlusions percutaneous coronary intervention: a case series. European Heart Journal - Case Reports, Published: 02 April 2018. Raja Hatem Matthew T Finn Robert F Riley  Moses Mathur, William L Lombardi Ziad A Ali Dimitri Karmpaliotis

●      Intravascular ultrasound analysis of intraplaque versus subintimal tracking in percutaneous intervention for coronary chronic total occlusions: One year outcomes. Finn MT, Doshi D, Cleman J, Song L, Maehara A, Hatem R, Redfors B, Kalra S, Fried JA, Liao M, Batres C, Moses JW, Parikh MA, Collins MB, Nazif TM, Fall KN, Green P, Kirtane AJ, Ali ZA, Leon MB, Mintz GS, Karmpaliotis D. Catheter Cardiovasc Interv. 2018 Nov 29. doi: 10.1002/ccd.27958. 

●      Novel Approaches to Define Outcomes in Coronary Revascularization. Ieroncig F, Breau JB, Bélair G, David LP, Noiseux N, Hatem R, Avram R. Can J Cardiol. 2019 Aug;35(8):967-982. doi: 10.1016/j.cjca.2018.12.016. Epub 2018 Dec 15. Review.

●      A case report of right ventricular compression from a septal haematoma during retrograde coronary intervention to a chronic total occlusion. Doshi D, Hatem R, Masoumi A, Karmpaliotis D. Eur Heart J Case Rep. 2019 Sep 1;3(3).pii: ytz089. doi: 10.1093/ehjcr/ytz089.

●      Outcomes of retrograde chronic total occlusion percutaneous coronary intervention: A report from the OPEN‐CTO registry Sanjog Kalra MD, MSc  Darshan Doshi MD, MS  James Sapontis MBBCh  Ioanna Kosmidou MD, PhD  Ajay J. Kirtane MD, SM  Jeffrey W. Moses MD  Robert F. Riley MD, MS  Philip Jones MS  William J. Nicholson MD  Adam C. Salisbury MD, MSc  William L. Lombardi MD  James M. McCabe MD  Ashish Pershad MD  Taishi Hirai MD  Emad Hakemi MD  Juan J. Russo MD  Megha Prasad MD  Yousif Ahmad MD  Raja Hatem MD  Fotis Gkargkoulas MD  John A. Spertus MD, MPH  R. Michael Wyman MD  Farouc Jaffer MD, PhD  Anthony Spaedy MD  Stephen Cook MD  Steven P. Marso MD  Karen Nugent RRT  Robert Federici MD  Robert W. Yeh MD, MBA  Martin B. Leon MD  Gregg W. Stone MD  Ziad A. Ali MD, DPhil  Manish A. Parikh MD  Akiko Maehara MD  David J. Cohen MD, MSc  Candido Batres MD  J. Aaron Grantham MD  Dimitri Karmpaliotis MD, PhD. First published: 02 September 2020

●  The self-made covered stent technique for treating coronary artery perforations. Journal of Cardiology Case Reports. Volume 3: 1-4. 2020Doshi, D., Hatem, R., Masoumi, A., Lembo, N. J., & Karmpaliotis, D.

●  Inaccuracy of brachial blood pressure and its potential impact on treatment and aortic blood pressure estimation. Kowalski C, Yang K, Charron T, Doucet M, Hatem R, Kouz R, Palisaitis D, Schampaert E, Terriault P, Tessier P, Agharazii M, Goupil R. J Hypertens. 2021 Aug 2. doi: 10.1097/HJH.0000000000002943. Epub ahead of print. PMID: 34343143.

● Global Chronic Total Occlusion Crossing Algorithm: JACC State-of-the-Art Review. Wu EB, Brilakis ES, Mashayekhi K, Tsuchikane E, Alaswad K, Araya M, Avran A, Azzalini L, Babunashvili AM, Bayani B, Behnes M, Bhindi R, Boudou N, Boukhris M, Bozinovic NZ, Bryniarski L, Bufe A, Buller CE, Burke MN, Buttner A, Cardoso P, Carlino M, Chen JY, Christiansen EH, Colombo A, Croce K, de Los Santos FD, de Martini T, Dens J, di Mario C, Dou K, Egred M, Elbarouni B, ElGuindy AM, Escaned J, Furkalo S, Gagnor A, Galassi AR, Garbo R, Gasparini G, Ge J, Ge L, Goel PK, Goktekin O, Gonzalo N, Grancini L, Hall A, Hanna Quesada FL, Hanratty C, Harb S, Harding SA, Hatem R, Henriques JPS, Hildick-Smith D, Hill JM, Hoye A, Jaber W, Jaffer FA, Jang Y, Jussila R, Kalnins A, Kalyanasundaram A, Kandzari DE, Kao HL, Karmpaliotis D, Kassem HH, Khatri J, Knaapen P, Kornowski R, Krestyaninov O, Kumar AVG, Lamelas PM, Lee SW, Lefevre T, Leung R, Li Y, Li Y, Lim ST, Lo S, Lombardi W, Maran A, McEntegart M, Moses J, Munawar M, Navarro A, Ngo HM, Nicholson W, Oksnes A, Olivecrona GK, Padilla L, Patel M, Pershad A, Postu M, Qian J, Quadros A, Rafeh NA, Råmunddal T, Prakasa Rao VS, Reifart N, Riley RF, Rinfret S, Saghatelyan M, Sianos G, Smith E, Spaedy A, Spratt J, Stone G, Strange JW, Tammam KO, Thompson CA, Toma A, Tremmel JA, Trinidad RS, Ungi I, Vo M, Vu VH, Walsh S, Werner G, Wojcik J, Wollmuth J, Xu B, Yamane M, Ybarra LF, Yeh RW, Zhang Q. J Am Coll Cardiol. 2021 Aug 24;78(8):840-853. doi: 10.1016/j.jacc.2021.05.055.

●  Conservative vs. Liberal Glycoprotein IIb-IIIa Antagonist Strategies in the Treatment of ST-Elevation Myocardial Infarction: A Dual-Center Analysis, Brian J Potter, Kashi Callichurn, Philippe Simard, Corrado De Marco, Payman Jamali, Yacine Saada, Alexis Matteau, Érick Schampaert, Samer Mansour, Raja Hatem. 10 January 2024, PREPRINT (Version 1) available at Research Square []

●      Reviewer Abstract JACC Case Reports 06-2020: Use of a totally occluded graft as a conduit for retrograde native artery recanalization" by Ioannis Tsiafoutis, Catherine Liontou, Michael Koutouzis, and Emmanouil Brilakis

●      Contributor and Co-Author chapter 30 of the Manual of Percutaneous Coronary Interventions - A Step by Step approach

●      Author of the chapter: Equipment requirement for Chronic Total Occlusion Percutaneous Coronary Intervention - Percutaneous Intervention for Coronary Chronic Total Occlusion

●      Contributor and Co-Author Chapters 26 and 30: Manual of CTO PCI 3rd Edition 2022


  • Cardiology
  • Preventive Medicine
  • Emergency Medicine

Areas of expertise

  • Coronary Heart Diseases
  • Cardiovascular Diseases
  • Cardiovascular System
  • Congenital Cardiopathies
  • Cardiomyopathy
  • Social Determinants of Cardiovascular Diseases
  • Prostheses and Vascular Substitutes
  • Heart Valve / Valvular Diseases
  • Heart Failure
  • Endocarditis
  • Cardiac Fibrosis
  • Angiogenesis
  • Lipid Disorders
  • Heart Transplantation