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Health Sciences; Medical Sciences

Laboratoire d'électropharmacologie

Centre de recherche hospitalier Faculté de médecine
Secondary number: 514 376-3330 #3587 (Information)
Secondary email: (Personne contact)



Research units

  • Centre de recherche de l'Institut de cardiologie de Montréal

Other Institutions and Research Units

  • Institut de cardiologie de Montréal (ICM)



At Université de Montreal


Projects and funding

Publications and presentations


1.  Luo X, Pan Z, Shan H, Xiao J, Sun X, Wang N, Lin H, Xiao L, Maguy A, Qi XY, Li Y, Gao X, Dong D, Zhang Y, Bai Y, Ai J, Sun L, Lu H, Luo XY, Wang Z, Lu Y, Yang B, Nattel S. MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation. J Clin Invest. 2013 May 1;123(5):1939-51. 

2.  Xiao L, Koopmann TT, Ordög B, Postema PG, Verkerk AO, Iyer V, Sampson KJ, Boink GJ, Mamarbachi MA, Varro A, Jordaens L, Res J, Kass RS, Wilde AA, Bezzina CR, Nattel S. Unique Cardiac Purkinje Fiber Transient Outward Current β-Subunit Composition: A Potential Molecular Link to Idiopathic Ventricular Fibrillation. Circ Res. 2013 May 10;112(10):1310-22.

3.  Dawson K, Wakili R, Ordög B, Clauss S, Chen Y, Iwasaki Y, Voigt N, Qi XY, Sinner MF, Dobrev D, Kääb S, Nattel S. MicroRNA29: a mechanistic contributor and potential biomarker in atrial fibrillation. Circulation. 2013 Apr 9;127(14):1466-75.

4. Harada M, Luo X, Qi XY, Tadevosyan A, Maguy A, Ordog B, Ledoux J, Kato T, Naud P, Voigt N, Shi Y, Kamiya K, Murohara T, Kodama I, Tardif JC, Schotten U, Van Wagoner DR, Dobrev D, Nattel S. Transient receptor potential canonical-3 channel-dependent fibroblast regulation in atrial fibrillation. Circulation. 2012 Oct 23;126(17):2051-64.

5.  Nattel S, Dobrev D. The multidimensional role of calcium in atrial fibrillation pathophysiology: mechanistic insights and therapeutic opportunities. Eur Heart J. 2012 Aug;33(15):1870-7.

6.  Dobrev D, Carlsson L, Nattel S. Novel molecular targets for atrial fibrillation therapy. Nat Rev Drug Discov. 2012 Mar 30;11(4):275-91.

7. Wakili R, Voigt N, Kääb S, Dobrev D, Nattel S. Recent advances in the molecular pathophysiology of atrial fibrillation. J Clin Invest. 2011 Aug;121(8):2955-68.

8.  Nattel S. New ideas about atrial fibrillation 50 years on. Nature. 2002 Jan 10;415(6868):219-26.

9. Kneller J, Zou R, Vigmond EJ, Wang Z, Leon LJ, Nattel S. Cholinergic atrial fibrillation in a computer model of a two-dimensional sheet of canine atrial cells with realistic ionic properties. Circ Res. 2002 May 17;90(9):E73-87.

10.  Li D, Fareh S, Leung TK, Nattel S. Promotion of atrial fibrillation by heart failure in dogs: atrial remodeling of a different sort. Circulation. 1999 Jul 6;100(1):87-95.


  • Cardiology
  • Pharmacology
  • Biochemistry
  • Molecular Biology
  • Applied Mathematics

Areas of expertise

  • Cardiovascular System
  • Model Building
  • Bioactive Molecules
  • Organic Molecules and Biomolecules
  • Bioprocesses and Biomedical systems