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Medical Sciences; Health Sciences

Chaire d’excellence en recherche du Canada sur l’éco-évopathie des microbes dans la nature

Chaire de recherche du Canada Faculté de médecine
Département de microbiologie, infectiologie et immunologie
Secondary number: 514 343-6111 #1903 (Laboratoire)
Secondary email: (Personne contact)



At Université de Montreal


Expertise description

Antibiotic resistance is one of the biggest threats to global health. Bacteriophages, which are the natural predators of bacteria, are being seriously considered as alternative therapies to antibiotics. The Canada Excellence Research Chair in Eco-Evo-Patho of Microbes in Nature, led by Dr. Frédérique Le Roux, aims to explore antibiotic resistance in marine bacteria, and interaction between these bacteria and their bacteriophages. Vibrios, which encompass human and animal bacterial pathogens, will be used as model systems, relying on translational research as part of the One Health priority area (the interdependence of human, animal and environmental health). Based on a unique collection of environmental isolates, Le Roux and her team will explore the diversity, mechanisms and evolution of antimicrobial resistance (antibiotic and heavy metal). They will seek to understand genome size heterogeneity in natural populations of vibrio and test the hypothesis that shellfish function as a hot spot for horizontal gene transfer. They will also explore the mechanisms involved in the co-evolution of bacteriophages and bacteria in nature, and how co-evolution affects the specificity of the bacteriophages and the pathogenicity of the bacteria. This work will shed light on innovative approaches to overcome antibiotic resistance.

Projects and funding

Publications and presentations


  • Microbiology
  • Bacteriology
  • Immunology
  • Infectious Diseases
  • Genomics

Areas of expertise

  • Antibiotics and Resistance
  • Globalization
  • Environmental Health
  • Chemical Pollutants
  • Genome
  • Genomic Damage and Repair
  • Technological Innovations
  • R&D and Innovation