My current research mainly concerns the cognitive and cerebral effects of different pediatric diseases and syndromes, such as epilepsy, infantile spasms, tuberous sclerosis complex (TSC), prematurity and congenital cardiac anomalies. In the laboratory, I use neuropsychological assessment and neuroimaging (optical imaging (NIRS), electroencephalography) and magnetoencephalography (MEG)) to better understand these pathologies and their impact on brain development, identify predictive markers for certain related disorders or developmental prognostics and develop pre-surgical assessment techniques suitable for use with these populations.

En plus d’être chercheuse au Centre de recherche du CHU Sainte-Justine, la Dre Anne Gallagher est professeure agrégée au Département de psychologie de l’Université de Montréal. Ses intérêts de recherche sont axés sur le développement cognitif et langagier de l’enfant. Plus spécifiquement, son programme de recherche se divise en deux volets: 1) Développement langagier typique au cours de la petite enfance ; 2) Les effets cognitifs et cérébraux de différentes maladies et syndromes pédiatriques, tels que l’épilepsie, les anomalies cardiaques congénitales et la prématurité. Au sein de son laboratoire, le Laboratoire d'Imagerie Optique en Neurodéveloppement (LIONlab), son équipe utilise l’évaluation neuropsychologique et l’imagerie cérébrale, notamment l’imagerie optique (NIRS) et l’électroencéphalographie (EEG), afin de mieux comprendre ces pathologies et leurs effets sur le développement du cerveau, identifier des marqueurs prédictifs du pronostic neurodéveloppemental et développer des techniques d’évaluation pré-chirurgicales pouvant être utilisées auprès de ces populations.

Publications des 7 dernières années:

1. *Hüsser A, Vannasing P, Tremblay J, Osterman B, Lortie A, Diadori P, Major P, Rossignol E, Roger K, Fourdain S, Provost A, Maalouf Y, Nguyen DK, Gallagher A. (accepted) Brain language networks and cognitive outcomes in children with frontotemporal lobe epilepsy. Frontiers in Human Neuroscience.
2. Smith ML, Puka K, Speechley KN, Ferro MA, Connolly MB, Major P, Gallagher A, Almubarak S, Hasal S, Ramachandrannair R, Andrade A, Xu Q, Leung E, Snead III OC, Widjaja E. (accepted). Trajectories of Parent Well-Being in Children with Drug-Resistant Epilepsy. Epilepsia.
3. *Provost S, Fourdain S, Vannasing P, Tremblay J, Roger K, García-Puented Y, Doussau A, Vinay MC, Von Siebenthal Z, Paquette N, Poirier N, Gallagher A. Relationship between 4-month functional brain network topology and 24-month neurodevelopmental outcome in children with congenital heart disease. European Journal of Paediatric Neurology 2023. 47:47-59. doi: 10.1016/j.ejpn.2023.09.005.
4. *Simard MN, *Lepage C, *Gaudet I, Paquette N, Doussau A, Poirier N, Beauchamp M, Côté S, Pinchefsky E, Brossard-Racine M, Mâsse B, Gallagher A. (in press) A parent-child yoga intervention for reducing attention deficits in children with congenital heart disease: The Yoga for Little Hearts Feasibility Study prior to a randomized controlled trial. BMJ Open. *co-first author
5. Gallagher A, Wallois F, Obrig H. (2023). fNIRS in pediatric clinical research: different pathophysiologies and promising clinical applications. Neurophotonics. 10(2): 023517.
6. Brossard-Racine M, Rampakakis E, Tardif CL, Gilbert G, White A, Luu TM, Gallagher A, Pinchefsky E, Montreuil T, Simard MN, Wintermark P. (2023) Long-term consequences of neonatal encephalopathy in the hypothermia era: protocol for a follow-up cohort study at 9 years of age. BMJ Open. 13. doi: 10.1136/bmjopen-2023-073063
7. Smith ML, Puka K, Speechley K, Ferro M, Connolly M, Major P, Gallagher A, Almubarak S, Hasal S, Ramachandrannair R, Andrade A, Xu Q, Leung E, Snead III O, Widjaja E. (2023). A longitudinal cohort study of mediators of health-related quality of life after pediatric epilepsy surgery or medical treatment. Epilepsia. 0: 0.
8. Fourdain S, Provost S, Tremblay J, Vannasing P, Doussau A, Caron-Desrocher L, Gaudet I, Roger K, Hüsser A, Dehaes M, Martínez-Montes E, Poirier N, Gallagher A. (2023). Functional brain connectivity after cardiac corrective surgery for critical congenital heart disease: a near-infrared spectroscopy study. Child Neuropsychology. 30: 1-21.
9. Lepage C, Gaudet I, Doussau A, Vinay MC, Gagner C, von Siebenthal Z, Poirier N, Simard MN, Paquette N, Gallagher A. (2023). The Role of Parenting Stress in Anxiety and Sleep Outcomes in Toddlers with Congenital Heart Disease. Frontiers in Pediatrics. 10: 1055526. 
10. Widjaja E, Puka K, Speechley K, Ferro M, Connolly M, Major P, Gallagher A, Almubarak S, Hasan S, Ramachandrannair R, Andrade A, Xu Q, Leung E, Snead III CO, Smith ML. (2023). Trajectory of healthrelated quality of life after pediatric epilepsy surgery: prospective multi-center cohort study. Journal of the American Medical Association (JAMA). 6(3). doi : 10.1001/jamanetworkopen.2023.2858.
11. Bonney E et al (35 contributors) (2023) The Global Brain Consortium’s GLAD White Paper: Challenges and Prospects for a Multi-National Children and Adolescents’ Brain Health Study. OSFpreprint. doi: 10.31219/osf.io/cq2uj 
12. Gaudet I, Paquette N, Doussau A, Poirier N, Simard MN, Beauchamp MH, Gallagher A. (2022). Social cognition and competence in preschoolers with congenital heart disease. Neuropsychology. 36(6): 552-564.
13. Roger K, Vannasing P, Tremblay J, Bringas Vega ML, Bryce CP, Rabinowitz AG, Valdés-Sosa PA, Galler JR, Gallagher A. (2022). Impact of early childhood malnutrition on the adult brain function: an ERP study. Frontiers in Neuroscience. 16: 884251 
14. Hüsser A, Caron-Desrochers L, Tremblay J, Vannasing P, Martínez-Montes E, Gallagher A. (2022). Parallel Factor Analysis (PARAFAC) for multidimensional decomposition of fNIRS data - A validation study. Neurophotonics. 9(4): 045004
15. Tremblay J, Martínez-Montes E, Hüsser A, Caron-Desrochers L, Pouliot P, Vannasing P, Gallagher A. (2022). LIONirs: flexible Matlab toolbox for fNIRS data analysis. Journal of Neuroscience Methods. 370 : 109487. doi: 10.1016/j.jneumeth.2022.109487
16. Bosch-Bayard J, Razzaq FA, Lopez-Naranjo C, Wang Y, Li M, Galan-Garcia L, Calzada-Reyes A, Virues-Alba T, Rabinowitz A, Suarez-Murias C, Guo Y, Sanchez-Castillo M, Roger K, Gallagher A, Prichep L, Anderson SG, Michel CM, Evans AC, Bringas-Vega ML, Galler J, Valdes-Sosa PA. (2022). Early Protein Energy Malnutrition distorts subsequent life-long developmental trajectories of the sources of EEG rhythmic activity. Neuroimage 254: 119144. doi: 10.1016/j.neuroimage.2022.119144
17. Gaudet I, Paquette N, Bernard C, Doussau A, Harvey J, Trudeau N, Beaulieu-Genest L, Pinchefsky E, Poirier N, Simard MN, Gallagher A. (2021). Neurodevelopmental outcome of children with congenital heart disease: a cohort study from infancy to preschool age. The Journal of Pediatrics. 239. doi: 10.1016/j.jpeds.2021.08.042.
18. Fourdain S, Simard MN, Dagenais L, Materassi M, Doussau A, Dehaes M, Goulet J, Gagnon K, Prud’homme J, Vobecky S, Poirier N, Carmant L, Gallagher A. (2021). Gross motor development of children with congenital heart disease receiving early surveillance and individualized intervention. Developmental Neurorehabilitation. 12. doi: 10.1080/17518423.2020.1711541. 
19. Lépine J, Gagnon K, Prud’homme J, Vinay MC, Doussaud A, Fourdain S, Provost S, Belval V, Bernard C,Gallagher A, Poirier N, Simard MN, on behalf of the CINC team. (2021). Utility of the ASQ-3 in screening for developmental delay in children with Congenital Heart Disease. Developmental Neurorehabilitation. 8. doi: 10.1080/17518423.2021.1960918.
20. Phillips NL, Widjaja E, Speechley K, Ferro M, Connolly M, Major P, Gallagher A, Ramachandrannais R, Almubarak S, Hasal S, Andrade A, Xu Q, Leung E, Snead III OC, Smith ML. (2021). Longitudinal changes in emotional functioning following pediatric resective epilepsy surgery: 2-year follow-up. Epilepsy and Behavior. 114. doi: 10.1016/j.yebeh.2020.107585.
21. Hüsser A, Fourdain S, Gallagher A. (2020). Neuropsychological Assessment. Handbook of Clinical Neurology; Neurocognitive Development. 174. doi: 10.1016/B978-0-444-64148-9.00017-X.
22. Citherlet D, Boucher O, Tremblay J, Robert M, Gallagher A, Bouthillier A, Lepore F, Nguyen D.K. (2020). Spatiotemporal Dynamics of Auditory Information Processing in the Insular Cortex: An Intracranial EEG Study using an Oddball Paradigm". Brain Structure and Function. 225. doi: 10.1007/s00429-020-02072-z. 
23. Fourdain S, Caron-Desrochers L, Simard MN, Provost S, Doussau A, Gagnon K, Dagenais L, Presutto E, Prud’homme J, Boudreault-Trudeau A, *Constantin IM, Desnoux B, Poirier N, Gallagher A, on behalf of the CINC team. (2020). Impacts of an Interdisciplinary Developmental Follow-up Program on Neurodevelopment in Congenital Heart Disease: the CINC Study.Frontiers in Pediatrics. 8. doi: 10.3389/fped.2020.539451.
24. Gaudet I, Gallagher A. (2020). Description and classification of neurodevelopmental disabilities. Handbook of Clinical Neurology; Neurocognitive Development. 173. doi: 10.1016/B978-0-444-64150-2.00001-0
25. Gaudet I, Hüsser A, Vannasing P, Gallagher A. (2020). Functional brain connectivity of language functions in children revealed by EEG and MEG: A systematic review. Frontiers in Human Neuroscience, 14: 62. doi: 10.3389/fnhum.2020.00062.
26. Fourdain S, St-Denis A, Harvey J, Carmant L, ­^†Gallagher A, ^†Trudeau N. Language development in children with congenital heart disease aged 12 to 24 months. European Journal of Pediatric Neurology 2019; 23(3): 491-499. doi : https://doi.org/10.1016/j.ejpn.2019.03.002  Co-auteur principal
27. Citherlet D, Boucher O, Tremblay J, Robert M, Gallagher A, Bouthillier A, Lepore F, Nguyen DK. Role of the insula in top-down processing: an intracranial EEG study using a visual oddball detection paradigm. Brain Structure and Function 2019; 224(6):2045-2059. Doi: 10.1007/s00429-019-01892-y
28. Tremblay J, Martínez-Montes, Vannasing P, Nguyen D, Sawan M, Lepore F, Gallagher A. Comparison of source localization techniques in diffuse optical tomography for fNIRS application using a realistic head model. Biomedical Optics Express 2018; 9(7): 2994-3016. doi: 10.1364/BOE.9.002994
29. Kassab A, Le Lan J, Vannasing P, Safi D, Dehbozorgi M, Pouliot P, Gallagher A, Lesage F, Sawan M, Nguyen DK. Multichannel Wearable NIRS-EEG System for Long-Term Clinical Monitoring. Human Brain Mapping 2018; 39: 7–23. doi:10.1002/hbm.23849
30. Major P, Lortie A, Dehaes M, Lodygensky GA, Gallagher A, Carmant L, Birca A. Periictal activity in cooled asphyxiated neonates with seizures. Seizure: European Journal of Epilepsy 2017; 43: 13-16. doi: 10.1016/j.seizure.2017.03.002
31. Gallagher A, Dagenais L, Doussau A, Décarie J-C, Materassi M, Gagnon K, Prud’homme J, Vobecky S, Poirier N, Carmant L. Significant motor improvement in an infant with congenital heart disease and a rolandic stroke: the impact of early intervention. Dev Neurorehabil. 2017;18:1–4. doi: 10.3109/17518423.2015.1132280
32. Birca A, Lortie A, Birca V, Decarie JC, Veilleux A, Gallagher A, Dehaes M, Lodygensky   GA, Carmant L. Rewarming affects EEG background in term newborns with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia. Clin Neurophysiol. 2016; 127(4):2087–94. doi: 10.1016/j.clinph.2015.12.013
33. Vannasing P, Cornaggia I, Vanasse C, Tremblay J, Diadori P, Perreault S, Lassonde M, Gallagher A. Potential brain language reorganization in a boy with refractory epilepsy: An fNIRS-EEG and fMRI comparison. Epilepsy Behav Case Reports. 2016; 5: 34–7. doi: 10.1016/j.ebcr.2016.01.006
34. Safi D, Béland R, Nguyen DK, Pouliot P, Mohamed IS, Vannasing P, Tremblay J, Lassonde M, Gallagher A. Recruitment of the left precentral gyrus in reading epilepsy: a multimodal neuroimaging study. Epilepsy Behav Case Reports. 2016; 5: 19–22. doi: 10.1016/j.ebcr.2016.01.003
35. Pirmoradi M, Jemel B, Gallagher A, Tremblay J, D’Hondt F, Nguyen DK, Béland R, Lassonde M. Verbal memory and verbal fluency tasks used for language localization and lateralization during magnetoencephalography. Epilepsy Res. 2016; 119: 1–9. doi: 10.1016/j.eplepsyres.2015.11.015
36. Gallagher A, Tremblay J, Vannasing P. Language mapping in children using resting-state functional connectivity: Comparison with a task-based approach. J Biomed Opt. 2016; 21(12): 125006-1-8. doi: 10.1117/1.JBO.21.12.125006
37. Kassab A, Tremblay J, Y. Poppe A, Létourneau-Guillon L, Gallagher A, Nguyen DK. Cerebral hemodynamic changes during limb-shaking tia: a near-infrared spectroscopy study. Neurology. 2016;86(12):1166–8. doi: 10.1212/WNL.0000000000002505
38. Vannasing P, Florea O, González-Frankenberger B, Tremblay J, Paquette N, Safi D, Wallois F, Lepore F, Béland R, Lassonde M, Gallagher A. Distinct hemispheric specializations for native and non-native languages in one-day-old newborns identified by fNIRS. Neuropsychologia. 2016;84:63–9. doi: 10.1016/j.neuropsychologia.2016.01.038
39. Fourdain S, Vanasse C-M, Poirier N, Carmant L, Gallagher A. Cardiopathies congénitales : physiopathologie, facteurs de risque et profils neuropsychologiques. Rev québécoise Psychol. 2016;37(2):3–20. 

Présentations des 5 dernières années:

1. (2023) Language brain response and neurodevelopmental outcome in preschoolers with congenital heart disease: a fNIRS study. Sarah Provost. World Congress of Pediactric Cardiology and Cardiac Surgery 2023 (WCPCCS2023), Washington DC, USA**Bronze Medal for the Best abstract competition WCPCCS2023, 3^rd out of 2800 abstracts
2. (2023) Using fNIRS in pediatric clinical populations. Symposium: NIRS in Movement Science, German Sport University, Cologne, Germany
3. (2023) Studying functional brain networks in at-risk pediatric populations. 11th European School on Multimodal Analysis of the Development of Brain Function, Amiens, France
4. (2023). Barbados Nutrition Study: the impact of infantile malnutrition on the adult brain function. Organization for Human Brain Mapping (OHBM) Satellite Symposium, Montreal
5. (2023) Toute la lumière sur le développement du cerveau. Organization for Human Brain Mapping (OHBM) Public Lectures, Montreal
6. (2023) LIONnirs Toolbox: a new tool for fNIRS data preprocessing and analyses. Julie Tremblay, pre-OHBM NIRx Workshop, Montreal
7. (2023). Adult Brain Function following Childhood Malnutrition: EEG-NIRS data. Global Brain Consortium (GBC) Annual Meeting, Virtual
8. (2023) LIONnirs Toolbox: a new tool for fNIRS data preprocessing and analyses. Julie Tremblay, NIRx Virtual Webinar Series, Virtual
9. (2023). Development of Language Brain Networks: typical and atypical trajectories. University of Trois-Rivière (UQTR) Annual Scientific Day, Trois-Rivières, Canada
10. (2022) fNIRS and EEG for studying the development of functional brain networks. 10th European School on Multimodal Analysis of the Development of Brain Function, Amiens, France
11. (2022) Altered fNIRS Language Networks in Children with Fronto-tempotal Epilepsy. Alejandra Hüsser, Society for functional Near Infrared Spectroscopy (sfNIRS) annual meeting, Boston
12. (2022). Social Outcomes in Preschooloers with Congenital Heart Disease: An intergrative perspective. Cardiac Neurodevelopmental Outcome Collaborative (CNOC) International Annual Meeting, Montreal
13. (2022). Harnessing individual variability of human brain systems across health and disease. Andrew Zalesky.Keynote Lecture Chair. Organization for Human Brain Mapping (OHBM) annual meeting, Glasgow
14. (2022). From the womb to wisdom. Session Chair. Organization for Human Brain Mapping (OHBM) annual meeting, Glasgow
15. (2022). Enlighten the Brain… What is Near Infrared Spectroscopy? NeuroQAM conference series, Montréal
16. (2021). fNIRS In Epilepsy: From Research To Clinic. Phetsamone Vannasing, Alejandra Hüsser, NIRx Virtual Webinar Series, Virtual
17. (2021). Neurodevelopmental outcome of children with congenital heart disease: a cohort study from infancy to preschool age. Cardiac Neurodevelopmental Outcome Collaborative (CNOC) International Annual Meeting (virtual), Virtual
18. (2021) Clinique, Enseignement et Recherche en Santé au Québec. Forum sur les vecteurs féminins du développement économique - Regards croisés Québec – Cuba, Ministère des Relations Internationales, Gouvernement du Québec, Virtual
19. (2021). Prenatal exposure to an unfamiliar language: A facilitation or competition effect for the newborn’s brain linguistic processing? Caron-Desrochers L, Paquette N, Vannasing P, Tremblay J, Roger K, Provost S, Fourdain S, Hüsser A, Petitpas L, Gervain J, Boucoiran I.  Society for functional Near Infrared Spectroscopy (sfNIRS) annual meeting, Virtual
20. (2021). Associations between functional brain connectivity networks in 4-month infants with congenital heart disease and their neurodevelopmental outcomes in early childhood. Sarah Provost, Solène Fourdain, International Organization of Psychophysiology, Virtual
21. (2021). Innovative Brain Recording Methods in Cognitive and Social Neuroscience - Co-chair Symposium. Sarah Lippé, International Organization of Psychophysiology, Virtual
22. (2021). Early markers of neurodevelopment in young children with CHD. Advances in behavioral and neuroimaging techniques for the study of neurodevelopment. A Cuba-Quebec-Mexico Workshop, Minister of International Relationship of Quebec, Virtual
23. (2021). Social outcomes in preschoolers with congenital heart disease (CHD): an integrative perspective. Gaudet I, Paquette N, Bernard C, Poirier N, Simard MN, Beauchamp M, Gallagher A, International Neuropsychological Society (INS) Annual Meeting, Virtual
24. (2021). NIRS-EEG : multimodal imaging in pediatric research. 8th European School of Cerebral Oxymetry and Optical Imaging, Amiens, France
25. (2020). Neuroimaging predictive markers of neurodevelopment. Global Brain Consortium (GBC), Varradero, Cuba
26. (2019). Impact of Childhood Epilepsy on Cognitive, Behavioral and Socio-Affective Functioning, MaryLou Smith, Canadian League Against Epilepsy (CLAE) Scientific Meeting, Winnipeg, Canada
27. (2019). Expérience de Montréal: Centre de suivi des cardiopathies congénitales, 9èmes Rencontres Francophones Multidisciplinaires des Cardiopathies Congénitales, Bordeaux, France  
28. (2019). Why using NIRS-EEG in pediatric populations? 7th European School of Cerebral Oxymetry and Optical Imaging, Amiens, France 
29. (2019). Does early intervention work? Cardiac Neurodevelopmental Outcome Collaborative (CNOC) Annual Meeting, Toronto, Canada
30. (2019). Neurodevelopmental profiles of children with common pediatric diseases: convulsive disorders and congenital heart disease, McGill University, Montreal, Canada
31. (2019). NIRS-EEG markers of infancy malnutrition: a pilot project part of the Barbados Nutrition Study, 11^e QBIN Scientific Day, Montreal, Canada
32. (2018). Maximizing the advantages of Near infrared spectroscopy (NIRS) in clinical settings: what else can be done?, 6th European Autumn School of Cerebral Oxymetry and Optical Imaging (fNIRS), Amiens, France
33. (2018). Toward the prediction and prevention of neurodevelopmental impairments in children with CHD, Pediatric Neurology Grand Round, SickKids Hospital, Toronto, Canada
34. (2018). Using NIRS-EEG as a clinical tool in children, Keynote Symposium, Organization for Human Brain Mapping (OHBM) annual meeting, Singapore
35. (2018). Neuroimagerie développementale du fonctionnement langagier, Keynote speaker, 7^e Journée scientifique annuelle pour le Consortium d'imagerie en neurosciences et santé mentale de Québec (CINQ), Québec, Canada
36. (2018). Le développement cognitif et visuel d’enfants nés prématurément : une perspective EEG, 40^e congrès annuel de la Société québécoise pour la recherche en psychologie (SQRP), Québec, Canada