Sergio Crespo-Garcia
- Professeur adjoint
-
École d'optométrie
Pavillon 3744, rue Jean-Brillant, room 230-35
Media
Laboratoire de Sergio Crespo-Garcia
Profile
Research expertise
Sergio Crespo-Garcia (he/him) develops his research in the field of retina degeneration and diabetes. His research interest revolves around the idea of better understanding the interactions of the cells that conform the blood vessels in the retina and how this translates to ocular disease.
Awards and recognitions
2022: HMR Foundation Publication Prize on Cell Metabolism 2021 (Canada)
2021: Montreal Diabetes Research Center Postdoctoral Award (Canada)
2021: Association for Research in Vision and Ophthalmology (ARVO) Travel Award (USA)
2021: Publication Prize Relève Étoile Jacqes-Genest on Cell Metabolism 2021 (Canada)
2021: Publication Prize Réseau Vision on Cell Metabolism 2021 (Canada)
2018-2021: Fonds de Recherche du Québec - Santé (FRQ-S) Postdoctoral Scholarship (Canada)
2018-2019: Hospital Maisonneuve-Rosemont (HMR) Foundation Postdoctoral Scholarship (Canada)
2017: Dr. Margot Engelmann Foundation Doctorate Award (Germany)
2016: International Society for Eye Research (ISER) Travel Award (Japan)
2013-2016: Marie Curie ITN Early Stage Researcher Scholarship (Germany)
2012-2013: “la Caixa” Foundation Masters Scholarship (Spain)
2012: IE University Promotion 2008 Valedictorian (Spain)
2012: IE University First Grade Honors Distinction (First-of-the-class) (Spain)
2011-2012: Spanish Ministry of Education Beca de Colaboración - Research Scholarship (Spain)
2010-2012: IE University Academic Excellence Scholarship (Spain)
2009-2010: IE University Honors Scholarship (Spain)
education
- 2022 — Post-doctorate — Biochimie médicale — Centre de recherche Hôpital Maisonneuve-Rosemont
- 2017 — Dr. rer. med. — Sciences biomédicales — Charité Universitätsmedizin Berlin
- 2016 — Post-graduate certificate — Ophtalmologie — University of Lincoln
- 2013 — M.Sc. — Biologie cellulaire — Universidad Complutense de Madrid
- 2012 — B.Sc. — Biologie et autres sciences connexes — IE University
For more information…
- 13-10-2021 Réseau de recherche en santé de la vision (RRSV) décerne ses prix à nos étudiants
- 11-02-2021 Découverte d'un nouveau médicament pour la rétinopathie diabétique
- 18-06-2021 Sergio Crespo-García’s research provides a little optimism in the possibility of treating diabetic retinopathy
- 2022-09-27 Sergio Crespo-Garcia: avoir à l’œil les maladies de la rétine
Affiliations and responsabilities
Research affiliations
Professional titles and affiliations
Titles: corporations and professional organizations
Canada Coordinator - Marie Curie Alumni Association North-America Chapter
Teaching and supervision
Recruitment in research
Recruiting talented undergraduate interns and M.Sc. candidates interested in translational research in the field of retina vascular disease. Send your CV and a cover letter to: sergio.crespo.garcia@umontreal.ca
Teaching
Courses taught (current session only)
- OPM-51502 – Travaux de recherche dirigés 5.2
- SCV-1151 – Sciences de la vision : Cerveau et vision
- SCV-2151 – Sciences de la vision: Physiologie de l'œil
Programs
Jury Member
Catarina Micaelo Fernandes (examen de synthèse)
Other educational activities
SCV1151: Sciences de la vision: cerveau et vision
SCV2151: Sciences de la vision: physiologie de l'oeil
SCV7003: Problèmatique en sciences de la vision
OPM4150: Introduction à la recherche
Projects
Research projects
Intercellular causality in the formation and degradation of the vascular glycocalyx
Intercellular causality in the formation and degradation of the vascular glycocalyx
Faulty perivascular metabolism predisposing to microvascular complications
Étude des interactions entre les mécanismes cellulaires qui sous-tendent les pathologies de la rétine
Novel mechanisms of homocysteine contributing to microvascular instability in diabetic retinopathy
Therapeutic merit and cellular mechanisms of folate during age-related macular degeneration.
Réseau de Recherche en Santé de la Vision (RRSV) - L’effet de l’hyperhomocystéinémie sur l’unité glial-périvasculaire dans la rétinopathie diabétique
Outreach
Publications and presentations
Publications
Crespo-Garcia S, Tsuruda PR, Dejda A, Ryan RD, Fournier F, ..., Dubrac A, Beausejour C, Armstrong S, Mallette FA, Yohn CB, Joyal JS, Marquess D, Beltran PJ, Sapieha P. 2021. Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination through BCL-xL inhibition. Cell Metabolism. Apr 6;33(4):818-832.e7
Crespo-Garcia S, Reichhart N, Skosyrski S, Kociok N, Joussen AM. 2021.Anti-inflammatory role of netrin-4 in diabetic retinopathy. Int. Journal Molecular Sciences. Apr 25;22(9):4481
Binet F, Cagnone G, Crespo-Garcia S, Hata M, Neault M, Dejda A, Wilson AM, Buscarlet M, ..., Côté JF, Andelfinger G, Rezende FA, Sennlaub F, Joyal J-S, Mallette FA, Sapieha P. 2020. Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy. Science. Aug 21;369(6506):eaay5356
Crespo-Garcia S, Reichhart N, Wigdahl J, Skosyrski S, Kociok N, Strauß, Joussen AM. 2019. Lack of netrin-4 alters vascular remodeling in the retina. Graefes Arch Clin Exp Ophthalmol. 257: 2179–2184.
Crespo-Garcia S, Reichhart N, Skosyrski S, Mr. Foddis M, Wu J, ..., Sassi C, Dirnagl U, Joussen AM, Strauss O. 2018. Individual and temporal variability of the retina after chronic bilateral common carotid artery occlusion (BCCAO). PloS One. 13(3)
Crespo-Garcia S, Corkhill C, Roubeix C, Davids AM, Kociok N, Strauss O, Joussen AM, Reichhart N. 2017. Inhibition of placenta growth factor reduces subretinal mononuclear phagocyte accumulation in choroidal neovascularization, Investig. Ophthalmol. Vis. Sci. 58(12): 4997-5006.
Reichhart N*, Crespo-Garcia S*, Haase N, Golic M, Skosyrski S, Rübsam A, ..., Bader M, Dechend R, Strauss O, Joussen AM. 2016. TetO rat as a new translational model for type 2 diabetic retinopathy by inducible insulin receptor knock-down, Diabetologia. 60(1):202-211 *First author
Kociok N *, Crespo-Garcia S*, Liang Y, Klein SV, Nürnberg C, Reichhart N, Skosyrski S, Moritz E, Maier AK, Brunken WJ, Strauss O, Koch M, Joussen AM. 2016. Lack of netrin-4 modulates pathologic neovascularization in the eye, Scientific Reports. 6:18828 *First author
Crespo-Garcia S, Reichhart N, Hernandez-Matas C, Zabulis X, Kociok N, Brockmann C, Joussen AM, Strauss O. 2015. In vivo analysis of the time and spatial activation pattern of microglia in the retina following laser-induced choroidal neovascularization. Experimental Eye Research. 139, 13-21
Disciplines
- Optometry
- Ophthalmology
- Cell Biology
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