Conférence de chimie avec le professeur Jieping Zhu de l'École Polytechnique Fédérale de Lausanne, Suisse.

Titre: ‘‘ Diverting Cycloalkenes to Polycyclic Indole Alkaloids’’

Endroit : G-715, Pavillon Roger-Gaudry

Heure : 11h00

Hôte : Professeure Lebel

Résumé : Indole alkaloids with broad skeleton diversity and important bioactivities have attracted attention of chemists for over a century. Indeed, the polycyclic structures of these natural products provided ideal test ground for the development of novel synthetic strategies and for the application of newly discovered reactions/transformations. In this talk, we will present a unified strategy that allowed us to accomplish the total synthesis of a number of structurally distinct indole alkaloids from simple cycloalkenes, emphasizing particularly on the design of integrated one-pot domino polycyclization processes.

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