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Health Sciences

Clarice Nishio

La physiologie et la physiopathologie du remodelage osseux au niveau de biomécanique orthodontique

Professeure agrégée

Faculté de médecine dentaire - Département de santé buccale

3535-3525 Chemin Queen-Mary, room 201


Research expertise

  • La physiologie et la physiopathologie du remodelage osseux au niveau de la biomécanique orthodontique et de la distraction osseuse.
  • La santé et le remodelage parodontal.
  • Les effets pharmacologiques et pathologies des tissus calcifiés.


  • Professeure agrégée, département de santé buccale, Faculté de médecine dentaire, Université de Montréal.
  • D.M.D, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brésil
  • M.Sc., Orthodontie. Université de Montréal, Montréal, Canada
  • Ph.D., Orthodontie, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brésil
  • Chercheure invitée, University of Hiroshima, Hiroshima, Japon
  • Post-doctorat, Biologie cellulaire, Université de Montréal, Montréal, Canada

Awards and recognitions

  • Subtelny, Baker, Eastman Teaching Fellowhip Award (American Association of Orthodontists Foundation, 2017-2019)
  • Eugene E. West Memorial Fellowship Award (American Association of Orthodontists Foundation, 2015-2016)
  • Prix d’excellence en enseignement Arto et Sona Demizjian en médecine dentaire – Faculté de médecine dentaire, Université de Montréal (2017)

Affiliations and responsabilities

Teaching and supervision

Student supervision

Theses and dissertation supervision (Papyrus Institutional Repository)


Research projects

2018 - 2019

Evaluation of the effects of osteoperforartion and piezocorticision on canine retraction: Ransomized controlled clinical trial.

Lead researcher : Clarice Nishio
Co-researchers : Robert Durand , Thomas Thong Nguyen
Funding sources: Alpha Omega Foundation of Canada
Grant programs:
2017 - 2019

Effect of Vitamin D on Bone Morphometry and on Stability of Orthodontic Tooth movement (OTM) in Rats

Lead researcher : Clarice Nishio
Co-researchers : Isabelle Villemure
Funding sources: American Association of Orthodontists Foundation 
Grant programs:
2015 - 2016

Effects on exogenous retinoic acid and corticotomy on inflammatory process and bone remodeling during tooth movement

Lead researcher : Clarice Nishio
Co-researchers : Florina Moldovan
Funding sources: American Association of Orthodontists Foundation 
Grant programs:
2014 - 2015

Évaluation de l'apport de la chirurgie minimalement invasive par piézocision segmentaire transcorticale sur le traitement orthodontique chez l'adulte: une étude pilote prospective (Fonds Émile-Beaulieu)

Lead researcher : Karine El Feghali
Co-researchers : Clarice Nishio
Funding sources: Fondation de l'Université Laval
Grant programs:


Publications and presentations


Strippoli J.; Schmittbuh M.; Durand R.; Rompré P.; Turkewicz J.; Voyer R.; Nishio C. (2020). Impact of piezo-corticision-assisted orthodontics on root resorption and alveolar bone: a prospective observational study. Clinical Oral Investigations. (Accepté).

Roy A.; Santos B. F; Rompré P.; Nishio C. (2019) Dental malocclusion among children with attention deficit and hyperactivity disorder (ADHD). Am J Orthod Dentofacial Orthop; (Accepté).

Strippoli J.; Durand R.; Schmittbuhl M.; Rompré P.; Voyer R.; Chandad F.; Nishio C. (2018) Piezo-corticision-assisted orthodontics : Efficiency, safety, and long-term evaluation of the inflammatory process. Am J Orthod Dentofacial Orthop; 155(5): 662-669.

Strippoli J.; Durand R.; Schmittbuhl M.; Voyer R.; Rompré P.; Nishio C. (2017) Pain and quality of life in patients undergoing guided piezocorticision- assisted orthodontic treatment. J. Clin. Orthod.; 51 (12): 792-799.

Nishio C; Rompré P; Moldovan F. (2017) Effect of exogenous retinoic acid on tooth movement and periodontium healing following tooth extraction in a rat model. Orthod. Craniofac. Res.; 20 Suppl 1 : 77-82.

Nishio C; Strippoli J; Durand R. (2017) Piezo-corticision-assisted orthodontics: Truth and myths. In: Kapila SD, Vig KWL, Huang GJ, eds. Anecdote, Expertise and Evidence: Applying New Knowledge to Everyday Orthodontics.Craniofacial Growth Series, Center for Human Growth and Development, The University of Michigan, Ann Arbor, MI; 53 : 147-165.

Gauthier M; Liu JL; Nishio C. (2016) Interactions médicamenteuses et remodelage osseux en orthodontie. Journal de L’Ordre des Dentistes du Québec; 53(1) : 44-7. 

Nishio C; Huynh N. (2016) Skeletal Malocclusion and Genetic Expression: an Evidenced-Based Review. Journal of Dental Sleep Medicine, 3 : 57-63.

Wazen RM; Moffatt P; Ponce KJ, Kuroda S; Nishio C. Nanci A. (2015) Inactivation of the odontogenic ameloblast-associated gene affects the integrity of the junctional epithelium and gingival healing. Eur Cell. Mater; 30: 187-99.

Nishio C; Wazen R; Moffatt P; Nanci A. (2013) Expression of odontogenic ameloblast-associated and amelotin in the junctional epithelium. Periodontology 2000; 63: 59-66.

Wazen RM; Kuroda S; Nishio C; Sellin K; Brunski JB; Nanci A. (2013) Gene expression profiling and histomorphometric analyses of the early bone healing response around nanotextured implants. Nanomedicine; 8: 1385-95.

Nishio C; Wazen R; Kuroda S; Moffatt P; Nanci A. (2010) Expression pattern of odontogenic ameloblast-associated and amelotin during formation and regeneration of the junctional epithelium. Eur Cell. Mater; 20: 393-402. 

Nishio C; Wazen R; Kuroda S; Moffatt P; Nanci A. (2010)Disruption of Periodontal Integrity Induces Expression of APIN by Epithelial Cell Rests of Malassez. J. Period. Res.; 45: 709-713.

Miguel-Neto AB; Nishio C; Mucha JN. (2010) Agreement evaluation of a newly proposed system   for malocclusion classification. Int. J. Odontostomat.; 4: 33-41.

Nishio C; Tanimoto K; Hirose M; Horiuchi S; Kuroda S; Tanne K; Tanaka E. (2009) Stress analysis in the mandibular condyle during prolonged clenching: a theorical approach with the finite element method. Proc. Inst. Mech. Eng. [H]; 223: 739-748.

Nishio C; Mendes AM; Almeida MAO; Tanaka E; Tanne K; Elias CN. (2009) Evaluation of aesthetic brackets’ resistance to torsional forces from archwire. Am. J. Orthod. Dentofacial Orthop.; 135: 42-8.

Potvin-Lapointe S; Nishio C; Wazen R; Macedo Crivelini M; Moffatt P; Nanci A. (2009) L’étude du genome de la dent permet la découverte de deux proteins – impact sur la santé parodontale. Journal de L’Ordre des Dentistes du Québec; 46: 13-15.

Nanci A; Wazen RM, Nishio C; Zalzal SF. (2008) Immunocytochemistry of matrix proteins in calcified tissues: functional biochemistry on section. Eur. J. Histochem.; 52: 201-14.
Nishio C. Formação do esmalte dentário, novas descobertas, novos horizontes. (2008) R. Dental Press Ortodon. Ortop. Facial.; 13(4): 17-18.

Ueki M; Tanaka N; Tanimoto T; Nishio C; Honda K; Lin YY; Tanne Y; Ohkuma S; Kamiya T; Tanaka E; Tanne K. (2008) The effect of mechanical loading on the metabolism of growth plate chondrocytes. Ann. Biomed. Eng.; 36:793-800.

Tanaka E; Sasaki A; Hasegawa T; Nishio C; Kawa N; Tanne K. (2008) Skeletal anchorage system for orthodontic correction of severe maxillary protrusion with previous experience of orthodontic treatment. Angle Orthod.; 78: 181-188.

Oliveira SR; Nishio C; Brunharo IHVP; Torres; Barreto S.; Quintão C.C.A. (2008) Correção da maloclusão Classe II com sobre mordida profunda. Odontologia SanMarquina; 11: 83-87.

Freire SM; Nishio C; Mendes AM; Quintão CCA; Almeida MAO. (2007) The relation between dental size and normal occlusion in Brazilians. Brazilian Dental Journal; 18: 253-257.

Galvão MAB; Cabral AC; Nishio C, Capelli Jr J. (2007) Orthodontic Management of a Transposed Maxillary Canine and Lateral Incisor. J. Clin. Orthod.; 41: 377-381.

Nishio C; Motta AFJ; Mucha JN; Elias CN. (2004) In vitro evaluation of frictional forces between archwires and ceramic brackets. Am. J. Orthod. Dentofac. Orthop.; 125: 56-64.

Silva DB; Nishio C; Bastos EP; Gleiser R. (1998) Cúspide em garage e dens in dente em um incisivo lateral girovertido: tratamento ortodôntico. J. Bras. Orthod. Orthop. Facial; 3: 71-75.


  • Dentistry
  • Oral Health
  • Physiology
  • Pharmacology
  • General Pathology

Areas of expertise

  • Orthodontics
  • Clinical research
  • Malocclusion
  • Orthodontic biomechanics
  • Cellular biology
  • Dentoalveolar surgery