Travaux sur la méningite causée par Streptococcus suis, un pathogène du porc (zoonose: transmise à l'Homme). Laboratoire de sérotypie: référence internationale. Laboratoire de diagnostic sérologique de la pleuropneumonie porcine (laboratoire de référence international).

Prof. Gottschalk was born and raised in Buenos Aires, Argentina, where he obtained a diploma as a veterinarian. He then arrived to Canada in 1987 where he obtained his PhD in microbiology and immunology from the University of Montreal. Since 2002 he is full professor at the department of pathology and microbiology of the Faculty of Veterinary Medicine of the University of Montreal. He obtained eight different national and international awards for his research. In addition, the University of Ghent (Belgium) granted him with a Honoris Causa in 2018 as a recognition for his career. Prof. Gottschalk is the director of the North American reference laboratory for swine pleuropneumonia (caused by Actinobacillus pleuropneumoniae) and Streptococcus suis. He is also a consultant for the WHO and FAO on human and swine diseases respectively caused by S. suis. Expertscape's PubMed-based algorithms placed him in the top 0.03% published authors worldwide on human and veterinarian Streptococcal infections (worldwide expert). Dr. Gottschalk has published more than 400 articles in peer-reviewed journals and more than 200 articles in professional journals. He has been requested as invited speaker to give more than 300 conferences in 36 countries around the world.

Directeur du laboratoire de diagnostic et développement de la sérologie porcine
Directeur du laboratoire international de référence de Streptococcus suis
Directeur du laboratoire international de référence pour la détection de l’infection causée par Actinobacillus pleuropneumoniae

Expert reconnu par l’Organisation Mondiale de la Santé pour les infections causées par S. suis chez l’homme
 

Roy D, Grenier D, Segura M, Mathieu-Denoncourt A, Gottschalk M. Recruitment of Factor H to the Streptococcus suis Cell Surface is Multifactorial. Pathogens (Basel, Switzerland). 2016;5(3).

Auger JP, Fittipaldi N, Benoit-Biancamano MO, Segura M, Gottschalk M. Virulence Studies of Different Sequence Types and Geographical Origins of Streptococcus suis Serotype 2 in a Mouse Model of Infection. Pathogens (Basel, Switzerland). 2016;5(3).

Auger, J.P., N. Meekhanon, M. Okura, M. Osaki, M. Gottschalk, T. Sekizaki, D. Takamatsu. 2015. Recovery of Streptococcus suis serotype 2 capsule in vivo. Emerging Infectious Diseases.

Okura, M., T. Nozawa, T. Watanabe, I. Nakagawa, D. Takamatsu, M. Osaki, T. Sekizaki, M. Gottschalk, S. Hamada, F. Maruyama. 2015. Miscellaneous genome sequencing reveals the characteristic genes of groups potentially hazardous to humans and the spread of antibiotic-resistance genes in Streptococcus suis. Journal of Bacteriology.

Athey T.B., S. Teatero, D. Takamatsu, J. Wasserscheid, K. Dewar, M. Gottschalk, N. Fittipaldi. Population structure and antimicrobial resistance profiles of Streptococcus suis serotype 2 sequence type 25 strains. PLoS One. 11: e0150908.

Hatrongjit, R., A. Kerdsin, M. Gottschalk, S. Hamada, K. Oishi, Y. Akeda. Development of a multiplex pcr assay to detect the major clonal complexes of Streptococcus suis relevant to human infection. Journal of Medical Microbiology. doi: 10.1099/jmm.0.000239.

Van Calsteren, M.R., G. Goyette-Desjardins, F. Gagnon, M. Okura, D. Takamatsu, R. Roy, M. Gottschalk, M. Segura. Explaining the serological characteristics of Streptococcus suis serotypes 1 and 1/2 from their capsular polysaccharide structure and biosynthesis. Journal of Biological Chemistry. Pii: jbc.M115.700716.

Sánchez Del Rey, V., J.F. Fernández-Garayzábal, L. Domínguez, M. Gottschalk, A.I. Vela. Screening of virulence-associated genes as a molecular typing method for characterization of Streptococcus suis isolates recovered from wild boars and pigs. Veterinary Journal. pii: S1090-0233(15)00478-5.

Vaillancourt, K., G. LeBel, M. Frenette, N. Fittipaldi, M. Gottschalk, D. Grenier. Purification and Characterization of Suicin 65, a Novel Class I Type B Lantibiotic Produced by Streptococcus suis. PLoS One. 10:e0145854.

Haas, B., K. Vaillancourt, L. Bonifait, M. Gottschalk, D. Grenier. Hyaluronate lyase activity of Streptococcus suis serotype 2 and modulatory effects of hyaluronic acid on the bacterium’s virulence properties. BMC Research Notes. 8: 722.

Meshkibaf, S., J. Fritz, M. Gottschalk, S.O. Kim. Preferential production of G-CSF by a protein-like Lactobacillus rhamnosus GR-1 secretory factor through activating TLR2-dependent signaling events without activation of JNKs. BMC Microbiology. 15: 238.

Auger, J.-P., M. Christodoulides, M. Segura, J. Xu, M. Gottschalk. Interactions of Streptococcus suis serotype 2 with human meningeal cells and astrocytes. BMC Research Notes. 8: 607.

Gottschalk, M., S. Lacouture. 2015. Canada : Distribution of Streptococcus suis (from 2012 to 2014) and Actinobacillus pleuropneumoniae (from 2011 to 2014) setorypes isolated from diseased pigs. Canadian Veterinary Journal. 56: 1093-1094. PMID: 26483588

Morales, B., Á. Ruiz, S. Lacouture, M. Gottschalk. Clonal distribution of Streptococcus suis isolated from diseased pigs in the central region of Chile. Canadian Journal of Veterinary Research. 79: 343-6.

Siqueira Soares, T.C., M. Gottschalk, S. Lacouture, J. Megid, P.E. Martins Ribolla, J.C. de Figueiredo Pantoja, A.C. Paes. 2015. Streptococcus suis in employees and the environment of swine slaughterhouses in São Paulo, Brazil: Occurrence, risk factors, serotype distribution, and antimicrobial susceptibility. The Canadian Journal of Veterinary Research. 79: 279-284.

Hatrongjit, R., A. Kerdsin, M. Gottschalk, D. Takeuchi, S. Hamada, K. Oishi, Y. Akeda. First human case report of sepsis due to infection with Streptococcus suis serotype 31 in Thailand. BMC Infectious Diseases. 15: 392.

Athey, T.B., J.P. Auger, S. Teatero, A. Dumesnil, D. Takamatsu, J. Wasserscheid, K. Dewar, M. Gottschalk, N. Fittipaldi. 2015. Complex population structure and virulence differences among serotype 2 Streptococcus suis strains belonging to sequence type 28. PLoS One. 10: e0137760.

Kerdsin, A., R. Hatrongjit, M. Gottschalk, D. Takeuchi, S. Hamada , Y. Akeda, K. Oishi. 2015. Emergence of Streptococcus suis serotype 9 infection in humans. Journal of Microbiology, Immunology and Infection. pii: S1684-1182(15)00822-1.

Pérez-Sancho, M., A.I. Vela, T. Garcia-Seco, M. Gottschalk, L. Dominguez, J.F. Fernández- Garayzábal. Assessment of MALDI-TOF MS as alternative tool for Streptococcus suis identification. Frontiers in Public Health. Doi: 10.3389/fpubh.2015.00202.

McGregor, G.F., M. Gottschalk, D.L. Godson, W. Wilkins, T.K. Bollinger. 2015. Disease risks associated with free-ranging wild boar in Saskatchewan. Canadian Veterinary Journal. 56: 839-844.

Bai, X., Z. Liu, S. Ji, M. Gottschalk, H. Zheng, J. Xu. 2015. Simultaneous detection of 33 Streptococcus suis serotypes using the luminex xTAG® assay™. Journal of Microbiology Methods. pii: S0167- 7012(15)30026-9.

Atanassov, C., L. Bonifait, M. Perivier, M. Gottschalk, D. Grenier. 2015. Candidate proteomic biomarkers for three genogroups of the swine pathogen Streptococcus suis serotype 2. BMC Microbiology. 15: 84.

Zheng, H., S. Ji, Z. Liu, R. Lan, Y. Huang, X. Bai, M. Gottschalk, J. Xu. 2015. Eight novel capsular polysaccharide synthesis gene loci identified in nontypeable Streptococcus suis isolates. Applied and Environmental Microbiology. 81: 4111-4119.

Roy, D., J.P. Auger, M. Segura, N. Fittipaldi, D. Takamatsu, O. Masatoshi, M. Gottschalk. 2015. Role of the capsular polysaccharide as a virulence factor for Streptococcus suis serotype 14. Canadian Journal of Veterinary Research. 79: 141-146.

Baroch, J.A., C.A. Gagnon, S. Lacouture, M. Gottschalk. 2015. Exposure of f US feral swine (Sus scrofa) in the United States to selected pathogens. Canadian Journal of Veterinary Research. 79: 74-78.

Vaillancourt, K., G. LeBel, M. Frenette, M. Gottschalk, D. Grenier. 2015. Suicin 3908, a new lantibiotic produced by a strain of Streptococcus suis serotype 2 isolated from a healthy carrier pig. Plos ONE. 10: e0117245.

Sánchez Del Rey, V., J.F. Fernández-Garayzábal, C. Bárcena, V. Briones, L. Domínguez, M. Gottschalk, A.I. Vela. 2014. Molecular typing of Streptococcus suis isolates from Iberian pigs: a comparison with isolates from common intensively-reared commercial pig breeds. Veterinary Journal. 202: 597-602.

Calzas, C., P. Lemire, G. Auray, V. Gerdts, M. Gottschalk, M. Segura. 2015. Antibody Response Specific to the Capsular Polysaccharide is Impaired in Streptococcus suis Serotype 2-Infected Animals. Infection and Immunity. 83: 441-453.

Wongsawan, K., M. Gottschalk, P. Tharavichitkul. 2015. Serotype- and virulence-associated gene profile of Streptococcus suis isolates from pig carcasses in Chiang Mai Province, Northern Thailand. Journal of Veterinary Medical Science. 77:233-236.

Muckle, A., A. López, M. Gottschalk, C. López-Méndez, J. Giles, L. Lund, M. Saab. 2014. Isolation of Streptococcus suis from two lambs with history of lameness. Canadian Veterinary Journal. 55: 946-949.

Espinosa, I., M. Áreas, M. Irian Percedo, E. Lobo, S. Martínez, M. Gottschalk. 2014. Serotyping of porcine Streptococcus suis recovered from diseased pigs in the western region of Cuba. Revista de Salud Animal. 36: 196-200.

Zheng, H., S. Ji, R. Lan, Z. Liu, X. Bai, W. Zhang, M. Gotschalk, J. Xu. 2014. Population analysis of Streptococcus suis isolates from slaughtered swine using minimum core genome sequence typing. Journal of Clinical Microbiology. 52: 3568-3572.

Haas B., L. Bonifait, K. Vaillancourt, S.J. Charette, M. Gottschalk, D. Grenier. 2014. Characterization of DNase activity and gene in Streptococcus suis and evidence for a role as virulence factor. BMC Research Notes. 7: 424.

LeBel, G., K. Vaillancourt, M. Frenette, M. Gottschalk, D. Grenier. 2014. Suicin 90-1330 from a nonvirulent strain of Streptococcus suis: a nisin-related lantibiotic active on Gram-positive swine pathogens. Applied and Environmental Microbiology. 80: 5484-5492.

Tharavichitkul, P., K. Wongsawan, N. Takenami, S. Pruksakorn, A. Fongcom, M. Gottschalk, B. Kanthawa, V. Supajatura, S. Takai. 2014. Correlation between PFGE Groups and Mrp / Epf / Sly Genotypes of Streptococcus Suis Serotype 2 in Northern Thailand. Journal of Pathogens. doi: 10.1155/2014/350416.

Sánchez del Rey, V., J.F. Fernández-Garayzábal, G. Mentaberre, V. Briones, S. Lavín, L. Domínguez, M. Gottschalk, A.I. Vela Alonso. 2014. Characterisation of Streptococcus suis isolates from wild boars (Sus scrofa). Veterinary Journal. 200: 464-467.

Gomez, E., C. Kennedy, M. Gottschalk, S. Cunningham, R. Patel, A. Virk. 2014 A Case of Streptococcus suis Prosthetic Joint Infection and Streptococcal Toxic Shock-like Syndrome in a United States Pig Farmer. Journal of Clinical Microbiology. 52: 2254-2258

Dang, Y., C. Lachance, Y. Wang, C.A. Gagnon, C. Savard, M. Segura, D. Grenier, M. Gottschalk. 2014. Transcriptional approach to study porcine tracheal epithelial cells individually or dually infected with swine influenza virus and Streptococcus suis. BMC Veterinary Research. 10: 86.

Kerdsin, A., Y. Akeda, R. Hatrongjit, U. Detchawna, T. Sekizaki, S. Hamada, M. Gottschalk, K. Oishi. 2014. Streptococcus suis Serotyping by a New Multiplex PCR. Journal of Medical Microbiology. 2014 63: 824-830.

Gottschalk, M., S. Lacouture. 2014. Actinobacillus pleuropneumoniae serotypes 3, 6, 8 and 15 isolated from diseased pigs in North America. Veterinary Record. 174: 452.

Soares, T.C., A.C. Paes, J. Megid, P.E. Ribolla, S. Paduan Kdos, M. Gottschalk. 2014. Antimicrobial susceptibility of Streptococcus suis isolated from clinically healthy swine in Brazil. Canadian Journal of Veterinary Research. 78: 145-149.

Goyette-Desjardins G, Auger JP, Xu J, Segura M, Gottschalk M. Streptococcus suis, an important pig pathogen and emerging zoonotic agent-an update on the worldwide distribution based on serotyping and sequence typing. Emerging microbes & infections. 2014;3(6):e45.

Charlebois A, Marois-Crehan C, Helie P, Gagnon CA, Gottschalk M, Archambault M. Genetic diversity of Mycoplasma hyopneumoniae isolates of abattoir pigs. Veterinary microbiology. 2014;168(2-4):348-56.

Van Calsteren MR, Gagnon F, Calzas C, Goyette-Desjardins G, Okura M, Takamatsu D, et al. Structure determination of Streptococcus suis serotype 14 capsular polysaccharide. Biochemistry and cell biology = Biochimie et biologie cellulaire. 2013;91(2):49-58.

Lachance C, Segura M, Gerber PP, Xu J, Gottschalk M. Toll-like receptor 2-independent host innate immune response against an epidemic strain of Streptococcus suis that causes a toxic shock-like syndrome in humans. PloS one. 2013;8(5):e65031.

Dominguez-Punaro MC, Koedel U, Hoegen T, Demel C, Klein M, Gottschalk M. Severe cochlear inflammation and vestibular syndrome in an experimental model of Streptococcus suis infection in mice. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 2012;31(9):2391-400.